Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAPGEF4 | Q8WZA2 | 10/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.37 |
| ▸ | CSNK1G2 | P78368 | 1/20 | 0.37 |
| ▸ | HTR1D | P28221 | 1/20 | 0.36 |
| ▸ | HTR1B | P28222 | 1/20 | 0.36 |
| ▸ | DHODH | Q02127 | 2/20 | 0.36 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.36 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.35 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22051001 | 0.87 | RAPGEF4 (0.55) | RAPGEF4TSHRCSNK1DCSNK1G2HTR1D | |
| SCHEMBL17858124 | 0.84 | RAPGEF4 (0.68) | RAPGEF4 | |
| SCHEMBL14981045 | 0.83 | RAPGEF4 (0.59) | RAPGEF4HTR1DHTR1BALDH1A1 | |
| SCHEMBL25964343 | 0.81 | RAPGEF4 (0.48) | RAPGEF4TSHRCSNK1DCSNK1G2HTR1D | |
| SCHEMBL23139819 | 0.81 | RAPGEF4 (0.50) | RAPGEF4AKR1C3AKR1C2 | |
| SCHEMBL20404366 | 0.78 | RAPGEF4 (0.70) | RAPGEF4TSHRHTR1DHTR1B | |
| SCHEMBL10296088 | 0.78 | ALDH1A1 (0.56) | RAPGEF4TSHRCSNK1DCSNK1G2DHODH | |
| SCHEMBL26510680 | 0.77 | CNR1 (0.47) | RAPGEF4 | |
| SCHEMBL19465405 | 0.76 | RAPGEF4 (0.43) | RAPGEF4TSHRCSNK1DCSNK1G2HTR1D | |
| SCHEMBL3220409 | 0.75 | RAPGEF4 (0.50) | RAPGEF4HTR1DHTR1BALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4123736-A1 | ORGANOELECTROLUMINESCENT DEVICE USING POLYCYCLIC AROMATIC DERIVATIVE COMPOUNDS | SFC Co., Ltd. (KR) | 2023-01-25 | — | — | EP | disclosed |