SCHEMBL22051001

SCHEMBL22051001

Cc1cc(C(C)(C)C)cc(C)c1Nc1ccc(C(C)(C)C)cc1

nearest known ligand 0.62

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
RAPGEF4 Q8WZA2 9/20 0.55
HTR1D P28221 1/20 0.45
HTR1B P28222 1/20 0.45
TSHR P16473 1/20 0.44
CSNK1D P48730 1/20 0.41
CSNK1G2 P78368 1/20 0.41
DHODH Q02127 2/20 0.41
POLB P06746 1/20 0.40
ALDH1A1 P00352 1/20 0.40
SLC2A1 P11166 1/20 0.40
AKR1C3 P42330 1/20 0.40
AKR1C2 P52895 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14981045 0.96 RAPGEF4 (0.59) RAPGEF4HTR1DHTR1BPOLBALDH1A1
SCHEMBL17858124 0.92 RAPGEF4 (0.68) RAPGEF4
SCHEMBL20404366 0.90 RAPGEF4 (0.70) RAPGEF4HTR1DHTR1BTSHR
SCHEMBL23139819 0.89 RAPGEF4 (0.50) RAPGEF4AKR1C3AKR1C2
SCHEMBL25964343 0.89 RAPGEF4 (0.48) RAPGEF4HTR1DHTR1BTSHRCSNK1D
SCHEMBL24913610 0.87 RAPGEF4 (0.47) RAPGEF4HTR1DHTR1BTSHRCSNK1D
SCHEMBL19465405 0.87 RAPGEF4 (0.43) RAPGEF4HTR1DHTR1BTSHRCSNK1D
SCHEMBL3220409 0.86 RAPGEF4 (0.50) RAPGEF4HTR1DHTR1BPOLBALDH1A1
SCHEMBL15312216 0.86 RAPGEF4 (0.49) RAPGEF4HTR1DHTR1BTSHRALDH1A1
SCHEMBL10296088 0.86 ALDH1A1 (0.56) RAPGEF4TSHRCSNK1DCSNK1G2DHODH

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 49 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12606563-B2 Organic light-emitting device LG CHEM, LTD. (KR) 2026-04-21 US disclosed
CN-116685593-B Compound and organic electroluminescent device comprising the same 出光兴产株式会社 2025-05-13 CN disclosed
US-20240244972-A1 COMPOUND AND AN ORGANIC ELECTROLUMINESCENCE DEVICE COMPRISING THE COMPOUND IDEMITSU KOSAN CO., LTC. (JP) 2024-07-18 US disclosed
US-20240244972-A1 COMPOUND AND AN ORGANIC ELECTROLUMINESCENCE DEVICE COMPRISING THE COMPOUND IDEMITSU KOSAN CO., LTC. (JP) 2024-07-18 US disclosed
EP-4381026-A1 COMPOUND AND AN ORGANIC ELECTROLUMINESCENCE DEVICE COMPRISING THE COMPOUND Idemitsu Kosan Co.,Ltd. (JP) 2024-06-12 EP disclosed
EP-3909958-B1 COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE COMPRISING SAME LG CHEMICAL LTD (KR) 2023-12-27 EP disclosed
CN-113906580-B Organic light-emitting element 株式会社LG化学 2023-12-08 CN disclosed
EP-3889236-B1 ORGANIC LIGHT-EMITTING ELEMENT USING POLYCYCLIC AROMATIC DERIVATIVE COMPOUND SFC CO LTD (KR) 2023-11-22 EP disclosed
US-11780856-B2 Compound and organic light-emitting device comprising same LG CHEM, LTD. (KR) 2023-10-10 US disclosed
US-11780856-B2 Compound and organic light-emitting device comprising same LG CHEM, LTD. (KR) 2023-10-10 US disclosed
WO-2021107681-A1 COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE COMPRISING SAME 주식회사 엘지화학 2021-06-03 WO disclosed
EP-3660024-B1 POLYCYCLIC AROMATIC COMPOUNDS AND ORGANIC ELECTROLUMINESCENT DEVICES USING THE SAME SFC CO LTD (KR) 2021-05-05 EP disclosed
US-10981938-B2 Polycyclic aromatic compounds and organic electroluminescent devices using the same SFC CO., LTD. (KR) 2021-04-20 US disclosed
EP-3792989-A1 ORGANIC LIGHT EMITTING DIODE INCLUDING BORON COMPOUNDS SFC Co., Ltd. (KR) 2021-03-17 EP disclosed
US-20210036233-A1 LIGHT EMITTING DIODE INCLUDING BORON COMPOUND SFC CO., LTD. (KR) 2021-02-04 US disclosed
US-20200395553-A1 ORGANIC ELECTROLUMINESCENT DEVICE SFC CO., LTD. (KR) 2020-12-17 US disclosed
EP-3750971-A1 ORGANIC ELECTROLUMINESCENT DEVICE SFC Co., Ltd. (KR) 2020-12-16 EP disclosed
EP-3288094-B1 LIGHT EMITTING ELEMENT AND COMPOSITION USED IN SAID LIGHT EMITTING ELEMENT SUMITOMO CHEMICAL CO (JP) 2020-06-10 EP disclosed
US-20200172558-A1 POLYCYCLIC AROMATIC COMPOUNDS AND ORGANIC ELECTROLUMINESCENT DEVICES USING THE SAME SFC CO., LTD. (KR) 2020-06-04 US disclosed
EP-3660024-A1 POLYCYCLIC AROMATIC COMPOUNDS AND ORGANIC ELECTROLUMINESCENT DEVICES USING THE SAME SFC Co., Ltd. (KR) 2020-06-03 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12606563-B2 Organic light-emitting device CYBA, CRY2, CRY1 RAPGEF4 4461/4885HTR1D 1406/4885HTR1B 1316/4885
US-20200172558-A1 POLYCYCLIC AROMATIC COMPOUNDS AND ORGANIC ELECTROLUMINESCENT DEVICES USING THE SAME DDC, TYR, DDT RAPGEF4 3473/4885HTR1D 2946/4885HTR1B 2629/4885
US-11780856-B2 Compound and organic light-emitting device comprising same CRY1, CRY2, LEF1 RAPGEF4 4008/4885HTR1D 1100/4885HTR1B 1433/4885
US-20240244972-A1 COMPOUND AND AN ORGANIC ELECTROLUMINESCENCE DEVICE COMPRISING THE COMPOUND DDT, ODC1, AOC2 RAPGEF4 3453/4885HTR1D 4075/4885HTR1B 3622/4885
US-10981938-B2 Polycyclic aromatic compounds and organic electroluminescent devices using the same DDC, TYR, DDT RAPGEF4 3473/4885HTR1D 2946/4885HTR1B 2629/4885
US-20200395553-A1 ORGANIC ELECTROLUMINESCENT DEVICE LEF1, AP2A2, CCNA1 RAPGEF4 2232/4885HTR1D 2964/4885HTR1B 1693/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.