Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RNASE1 | P07998 | 1/20 | 0.64 |
| ▸ | TK1 | P04183 | 6/20 | 0.64 |
| ▸ | LMNA | P02545 | 2/20 | 0.59 |
| ▸ | TSHR | P16473 | 2/20 | 0.59 |
| ▸ | ALB | P02768 | 1/20 | 0.59 |
| ▸ | PKM | P14618 | 1/20 | 0.59 |
| ▸ | BLM | P54132 | 1/20 | 0.59 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.59 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28338723 | 0.91 | TK1 (0.67) | RNASE1TK1LMNATSHRALB | |
| SCHEMBL6224637 | 0.91 | TK1 (0.67) | RNASE1TK1LMNATSHRALB | |
| SCHEMBL2056647 | 0.89 | RNASE1 (0.69) | RNASE1TK1LMNATSHRALB | |
| SCHEMBL23734388 | 0.89 | RNASE1 (0.61) | RNASE1TK1LMNATSHRALB | |
| SCHEMBL26571124 | 0.88 | RNASE1 (0.68) | RNASE1TK1LMNATSHRALB | |
| SCHEMBL24059045 | 0.88 | RNASE1 (0.68) | RNASE1TK1LMNATSHRALB | |
| SCHEMBL6248265 | 0.88 | RNASE1 (0.68) | RNASE1TK1LMNATSHRALB | |
| SCHEMBL16360133 | 0.88 | RNASE1 (0.68) | RNASE1TK1LMNATSHRALB | |
| SCHEMBL19662165 | 0.87 | TK1 (0.61) | RNASE1TK1LMNATSHRALB | |
| SCHEMBL6832175 | 0.87 | RNASE1 (0.67) | RNASE1TK1LMNATSHRALB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230028321-A1 | NUCLEOTIDE DERIVATIVES AND METHODS OF USE THEREOF | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) | 2023-01-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230028321-A1 | NUCLEOTIDE DERIVATIVES AND METHODS OF USE THEREOF | POLRMT, NSUN2, NUDT1 | RNASE1 276/4885TK1 244/4885LMNA 432/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.