SCHEMBL24913686

SCHEMBL24913686

CC(C)(C)c1cc(-c2ccc(N)cc2)cc(C(C)(C)C)c1

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RXRB P28702 7/20 0.55
RXRA P19793 6/20 0.55
RXRG P48443 3/20 0.55
ALDH1A1 P00352 3/20 0.50
CYP3A4 P08684 2/20 0.50
TDP1 Q9NUW8 2/20 0.50
TP53 P04637 2/20 0.50
MAPT P10636 2/20 0.48
KDM4E B2RXH2 1/20 0.48
GAA P10253 1/20 0.48
NPC1 O15118 3/20 0.47
RAB9A P51151 3/20 0.47
HPGD P15428 1/20 0.47
MAPK1 P28482 1/20 0.47
KIF11 P52732 4/20 0.46
POLB P06746 1/20 0.43
TAAR1 Q96RJ0 1/20 0.42
HSD17B10 Q99714 1/20 0.42
GABRA1 P14867 1/20 0.41
GABRB2 P47870 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL414084 0.88 RXRB (0.65) RXRBRXRARXRGMAPTKDM4E
SCHEMBL4526927 0.88 RXRB (0.65) RXRBRXRARXRGMAPTKDM4E
SCHEMBL2655921 0.83 NPC1 (0.64) ALDH1A1CYP3A4TDP1TP53MAPT
SCHEMBL22539620 0.83 NPC1 (0.64) ALDH1A1CYP3A4TDP1TP53MAPT
SCHEMBL22780707 0.83 RXRA (0.47) RXRBRXRARXRGALDH1A1TP53
SCHEMBL22960107 0.81 MAPT (0.52) RXRBRXRARXRGALDH1A1TP53
SCHEMBL30720010 0.81 MAPT (0.52) RXRBRXRARXRGALDH1A1TP53
SCHEMBL13483895 0.81 KIF11 (0.61) RXRBRXRAALDH1A1CYP3A4TDP1
SCHEMBL13539901 0.80 RXRB (0.58) RXRBRXRARXRGALDH1A1TP53
SCHEMBL13871685 0.80 RXRB (0.58) RXRBRXRARXRGALDH1A1TP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230132685-A1 ORGANIC ELECTROLUMINESCENT ELEMENT AND FUSED POLYCYCLIC COMPOUND FOR ORGANIC ELECTROLUMINESCENT ELEMENT SAMSUNG DISPLAY CO., LTD. (KR) 2023-05-04 US disclosed
US-20230132685-A1 ORGANIC ELECTROLUMINESCENT ELEMENT AND FUSED POLYCYCLIC COMPOUND FOR ORGANIC ELECTROLUMINESCENT ELEMENT SAMSUNG DISPLAY CO., LTD. (KR) 2023-05-04 US disclosed
US-20230029353-A1 HOLE-TRANSPORT LAYER MATERIAL, ELECTRON-BLOCKING LAYER MATERIAL, ELECTRON-TRANSPORT LAYER MATERIAL, HOLEBLOCKING LAYER MATERIAL, LIGHT-EMITTING DEVICE, LIGHTEMITTING APPARATUS, ELECTRONIC DEVICE, AND LIGHTING DEVICE SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2023-01-26 US disclosed
CN-115417775-A Material for hole transport layer, material for electron blocking layer, material for electron transport layer, material for hole blocking layer, and light-emitting device 株式会社半导体能源研究所 2022-12-02 CN disclosed
CN-115197073-A Organic compound, light-emitting device, light-emitting apparatus, electronic device, and lighting apparatus 株式会社半导体能源研究所 2022-10-18 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230029353-A1 HOLE-TRANSPORT LAYER MATERIAL, ELECTRON-BLOCKING LAYER MATERIAL, ELECTRON-TRANSPORT LAYER MATERIAL, HOLEBLOCKING LAYER MATERIAL, LIGHT-EMITTING DEVICE, LIGHTEMITTING APPARATUS, ELECTRONIC DEVICE, AND LIGHTING DEVICE GOLT1B, CLTB, LAMP2 RXRB 3162/4885RXRA 4110/4885RXRG 3091/4885
US-20230132685-A1 ORGANIC ELECTROLUMINESCENT ELEMENT AND FUSED POLYCYCLIC COMPOUND FOR ORGANIC ELECTROLUMINESCENT ELEMENT LEF1, CTCF, PIEZO1 RXRB 3819/4885RXRA 2852/4885RXRG 3453/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.