SCHEMBL24913951

SCHEMBL24913951

CN1CC(Nc2cccc3c2CNCC3)CCC1=O

nearest known ligand 0.39

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
PNMT P11086 5/20 0.39
PIM1 P11309 1/20 0.39
PIM2 Q9P1W9 1/20 0.39
SRD5A1 P18405 2/20 0.36
PRCP P42785 1/20 0.36
HRH3 Q9Y5N1 1/20 0.34
TIPARP Q7Z3E1 1/20 0.33
LTA4H P09960 1/20 0.33
PRMT5 O14744 1/20 0.33
BRD4 O60885 1/20 0.32
ATAD2 Q6PL18 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL31062418 0.99 PIM1 (0.38) PNMTPIM1PIM2SRD5A1PRCP
SCHEMBL24914253 0.89 PNMT (0.40) PNMTPRCPHRH3PRMT5BRD4
SCHEMBL24914065 0.89 PNMT (0.40) PNMTPRCPHRH3PRMT5BRD4
SCHEMBL24913839 0.89 PNMT (0.40) PNMTPRCPHRH3PRMT5BRD4
Hydrochloric Acid SCHEMBL31062510 0.88 PNMT (0.39) PNMTPRCPHRH3PRMT5BRD4
SCHEMBL24914018 0.83 PNMT (0.38) PNMTPRCPHRH3TIPARPPRMT5
SCHEMBL24914013 0.82 PNMT (0.41) PNMTPRCPHRH3
Hydrochloric Acid SCHEMBL31062478 0.82 PNMT (0.37) PNMTPRCPHRH3TIPARPPRMT5
Hydrochloric Acid SCHEMBL31062514 0.81 PNMT (0.40) PNMTPRCPHRH3
SCHEMBL24914012 0.80 PNMT (0.44) PNMTPRCPHRH3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240293392-A1 INHIBITOR COMPOUNDS Neophore Limited (GB) 2024-09-05 US disclosed
WO-2023002165-A1 INHIBITOR COMPOUNDS Neophore Limited (GB) 2023-01-26 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240293392-A1 INHIBITOR COMPOUNDS MSH2, PMS2, MSH6 PNMT 1748/4885PIM1 3908/4885PIM2 3875/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.