SCHEMBL24914013

SCHEMBL24914013

CN1CCC(Nc2cccc3c2CNCC3)C1

nearest known ligand 0.42

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
PNMT P11086 5/20 0.41
PRCP P42785 1/20 0.39
HRH3 Q9Y5N1 1/20 0.38
KAT2B Q92831 2/20 0.38
NSD2 O96028 1/20 0.36
PIK3CD O00329 1/20 0.34
PIK3C2B O00750 1/20 0.34
MTOR P42345 1/20 0.34
PIK3CG P48736 1/20 0.34
CD44 P16070 1/20 0.34
MAOB P27338 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL31062514 0.99 PNMT (0.40) PNMTPRCPHRH3KAT2BNSD2
SCHEMBL24914012 0.94 PNMT (0.44) PNMTPRCPHRH3KAT2BNSD2
Hydrochloric Acid SCHEMBL31062565 0.92 PNMT (0.43) PNMTPRCPHRH3NSD2CD44
SCHEMBL31062557 0.82 PIM1 (0.40) PNMTPRCPNSD2
SCHEMBL24913861 0.82 PIM1 (0.40) PNMTPRCPNSD2
SCHEMBL31062507 0.82 PIM1 (0.40) PNMTPRCPNSD2
SCHEMBL24913863 0.82 PIM1 (0.40) PNMTPRCPNSD2
SCHEMBL24913951 0.82 PNMT (0.39) PNMTPRCPHRH3
SCHEMBL24914018 0.81 PNMT (0.38) PNMTPRCPHRH3PIK3CDPIK3C2B
Hydrochloric Acid SCHEMBL31062418 0.81 PIM1 (0.38) PNMTPRCPHRH3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240293392-A1 INHIBITOR COMPOUNDS Neophore Limited (GB) 2024-09-05 US disclosed
WO-2023002165-A1 INHIBITOR COMPOUNDS Neophore Limited (GB) 2023-01-26 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240293392-A1 INHIBITOR COMPOUNDS MSH2, PMS2, MSH6 PNMT 1748/4885PRCP 2632/4885HRH3 1142/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.