SCHEMBL24914009

SCHEMBL24914009

CC(=O)N1CC(N(C)c2cccc3c2CNCC3)C1

nearest known ligand 0.40

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
PNMT P11086 7/20 0.40
PRCP P42785 1/20 0.37
NOTUM Q6P988 2/20 0.34
TIPARP Q7Z3E1 1/20 0.33
CD44 P16070 1/20 0.33
MAOB P27338 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29168639 0.78 NOTUM (0.44) NOTUM
SCHEMBL30156764 0.76 ALDH1A1 (0.37)
SCHEMBL24913943 0.76 ALDH1A1 (0.37)
Hydrochloric Acid SCHEMBL29168604 0.76 ALDH1A1 (0.37)
Hydrochloric Acid SCHEMBL29168609 0.76 ALDH1A1 (0.37)
SCHEMBL24913833 0.73 PNMT (0.41) PNMTPRCPTIPARPCD44MAOB
SCHEMBL24914007 0.73 NR1H2 (0.46) NOTUM
SCHEMBL30156843 0.73 NR1H2 (0.46) NOTUM
Hydrochloric Acid SCHEMBL29168701 0.72 PNMT (0.40) PNMTPRCPTIPARPCD44MAOB
SCHEMBL31062507 0.69 PIM1 (0.40) PNMTPRCP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240293392-A1 INHIBITOR COMPOUNDS Neophore Limited (GB) 2024-09-05 US disclosed
CN-117693507-A Inhibitor compounds 奈奥芬莱有限公司 2024-03-12 CN disclosed
WO-2023002165-A1 INHIBITOR COMPOUNDS Neophore Limited (GB) 2023-01-26 WO disclosed
WO-2023002165-A1 INHIBITOR COMPOUNDS Neophore Limited (GB) 2023-01-26 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240293392-A1 INHIBITOR COMPOUNDS MSH2, PMS2, MSH6 PNMT 1748/4885PRCP 2632/4885NOTUM 4846/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.