SCHEMBL2491432

SCHEMBL2491432

O=C(CC(=O)c1ccc(F)cc1)c1ccc(F)cc1

nearest known ligand 0.69

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PLOD2 O00469 1/20 0.69
NPC1 O15118 4/20 0.67
RAB9A P51151 4/20 0.67
PTPN1 P18031 1/20 0.67
MEN1 O00255 4/20 0.66
KMT2A Q03164 4/20 0.66
MAPT P10636 3/20 0.66
SMN1; SMN2 Q16637 3/20 0.66
HPGD P15428 2/20 0.66
ALOX12 P18054 2/20 0.66
HTT P42858 2/20 0.66
NPSR1 Q6W5P4 1/20 0.66
CES1 P23141 2/20 0.59
CES2 O00748 1/20 0.59
HTR7 P34969 1/20 0.57
KDM4E B2RXH2 2/20 0.56
ALOX15 P16050 2/20 0.56
CYP3A4 P08684 1/20 0.56
MAPK1 P28482 1/20 0.56
TDP1 Q9NUW8 1/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30114978 0.93 PLOD2 (0.62) PLOD2NPC1RAB9APTPN1MEN1
SCHEMBL10731900 0.91 MEN1 (0.74) PLOD2NPC1RAB9APTPN1MEN1
SCHEMBL11175600 0.88 PLOD2 (0.62) PLOD2NPC1RAB9APTPN1MEN1
SCHEMBL904555 0.88 PLOD2 (0.62) PLOD2NPC1RAB9APTPN1MEN1
SCHEMBL3846985 0.86 PLOD2 (0.60) PLOD2NPC1RAB9APTPN1MEN1
SCHEMBL28991602 0.86 PLOD2 (0.60) PLOD2NPC1RAB9APTPN1MEN1
Fluoride SCHEMBL11175607 0.86 PLOD2 (0.60) PLOD2NPC1RAB9APTPN1MEN1
SCHEMBL120769 0.86 PLOD2 (0.60) PLOD2NPC1RAB9APTPN1MEN1
SCHEMBL28972880 0.85 MEN1 (0.65) PLOD2NPC1RAB9APTPN1MEN1
SCHEMBL26134425 0.85 MEN1 (0.65) PLOD2NPC1RAB9APTPN1MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 71 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122054902-A Metal halide perovskite film, preparation method thereof and photovoltaic device 南京工业大学 2026-05-15 CN claimed
CN-122011362-A Polyaryletherketone copolymer with high Tg and low Tm, preparation method thereof and composite material 江苏君华特种高分子材料股份有限公司 2026-05-12 CN claimed
CN-119640035-A Composite extractant and application thereof in separating and recycling lithium from lithium precipitation mother liquor 江西赣锋锂业集团股份有限公司 2025-03-18 CN claimed
CN-115975179-A Preparation method of alkyl structure-containing polyaryletherketone resin, alkyl structure-containing polyaryletherketone resin and application 中国科学院大连化学物理研究所 2023-04-18 CN claimed
US-5877210-A CONTROLLING IMMUNE RESPONSE BRISTOL-MYERS SQUIBB COMPANY (US) 1999-03-02 US claimed
US-5583242-A VANADYL COMPLEXES BRISTOL-MYERS SQUIBB COMPANY (US) 1996-12-10 US claimed
US-5565491-A FOR TREATMENT OF DISEASES MARKED BY MALIGNANT PROLIFERATION OF B CELLS, SUCH AS LEUKEMIA AND LYMPHOMAS; ANTICARCINOGENIC AGENTS BRISTOL-MYERS SQUIBB COMPANY (US) 1996-10-15 US claimed
US-5316909-A Quantitative analysis WALLAC OY (FI) 1994-05-31 US claimed
WO-1992016840-A1 LANTHANID FLUORESCENCE ASSAY OY DATACITY CENTER AB (FI) 1992-10-01 WO claimed
US-4857475-A Labelled and labellable reagents for fluorometric assays Ekins, Roger Philip (GB) 1989-08-15 US claimed
CN-122054902-A Metal halide perovskite film, preparation method thereof and photovoltaic device 南京工业大学 2026-05-15 CN disclosed
CN-122011362-A Polyaryletherketone copolymer with high Tg and low Tm, preparation method thereof and composite material 江苏君华特种高分子材料股份有限公司 2026-05-12 CN disclosed
CN-119640035-A Composite extractant and application thereof in separating and recycling lithium from lithium precipitation mother liquor 江西赣锋锂业集团股份有限公司 2025-03-18 CN disclosed
CN-119640035-A Composite extractant and application thereof in separating and recycling lithium from lithium precipitation mother liquor 江西赣锋锂业集团股份有限公司 2025-03-18 CN disclosed
CN-117466817-A Preparation method of polysubstituted pyrazole derivative 华侨大学 2024-01-30 CN disclosed
WO-1995020390-A1 USE OF VANADIUM MOLYBDENUM OR TUNGSTEN COMPLEXES FOR CONTROLLING CELLULAR PROLIFERATION BRISTOL-MYERS SQUIBB COMPANY (US) 1995-08-03 WO disclosed
US-4401474-A Pyrolytic coating reactant for defect and durability control PPG INDUSTRIES, INC. (US) 1983-08-30 US disclosed
US-4292347-A Pyrolytic coating reactant for defect and durability control PPG INDUSTRIES, INC. (US) 1981-09-29 US disclosed
US-4147556-A Nonflammable beta diketonate composition PPG INDUSTRIES, INC. (US) 1979-04-03 US disclosed
US-4123268-A OF DIKETONES; ELECTROGRAPHY ADDRESSOGRAPH-MULTIGRAPH CORPORATION (US) 1978-10-31 US disclosed