Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 6/20 | 0.74 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.74 |
| ▸ | MAPT | P10636 | 4/20 | 0.74 |
| ▸ | HPGD | P15428 | 3/20 | 0.74 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.74 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.74 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.74 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.74 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.74 |
| ▸ | CES1 | P23141 | 1/20 | 0.74 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.74 |
| ▸ | NPC1 | O15118 | 5/20 | 0.68 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.68 |
| ▸ | HTT | P42858 | 1/20 | 0.68 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.68 |
| ▸ | RAB9A | P51151 | 4/20 | 0.64 |
| ▸ | PLOD2 | O00469 | 3/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.59 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.59 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28972880 | 0.94 | MEN1 (0.65) | MEN1KMT2AMAPTHPGDCYP3A4 | |
| SCHEMBL2491432 | 0.91 | PLOD2 (0.69) | MEN1KMT2AMAPTHPGDCYP3A4 | |
| SCHEMBL2005451 | 0.89 | MEN1 (0.94) | MEN1KMT2AMAPTHPGDCYP3A4 | |
| SCHEMBL4485908 | 0.87 | RAB9A (0.69) | MEN1KMT2AMAPTHPGDCYP3A4 | |
| Dibenzoylmethane SCHEMBL1704711 | 0.86 | MEN1 (1.00) | MEN1KMT2AMAPTHPGDCYP3A4 | |
| Dibenzoylmethane SCHEMBL39582 | 0.86 | MEN1 (1.00) | MEN1KMT2AMAPTHPGDCYP3A4 | |
| Dibenzoylmethane SCHEMBL10356288 | 0.86 | MEN1 (1.00) | MEN1KMT2AMAPTHPGDCYP3A4 | |
| SCHEMBL904555 | 0.84 | PLOD2 (0.62) | MEN1KMT2AMAPTHPGDCYP3A4 | |
| SCHEMBL30114978 | 0.84 | PLOD2 (0.62) | MEN1KMT2AMAPTHPGDCYP3A4 | |
| Dibenzoylmethane SCHEMBL28463188 | 0.84 | KMT2A (0.85) | MEN1KMT2AMAPTHPGDCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105254483-A | Method for preparing 2-methyl-1,3-dicarbonyl derivative | UNIV SOOCHOW | 2016-01-20 | — | — | CN | claimed |
| CN-114890881-B | Method for simply synthesizing allyl dicarbonyl compound | 南阳师范学院 | 2023-06-02 | — | — | CN | disclosed |
| CN-114890881-A | Method for simply synthesizing allyl dicarbonyl compound | 南阳师范学院 | 2022-08-12 | — | — | CN | disclosed |
| CN-110746278-B | Nonmetal-catalyzed method for preparing 1, 3-diketone compound based on alkynone | 四川轻化工大学 | 2022-07-12 | — | — | CN | disclosed |
| CN-109776293-B | Method for preparing 1, 3-diketone compound from alkynone | 温州大学 | 2022-04-05 | — | — | CN | disclosed |
| CN-111393269-A | Method for synthesizing 1, 3-dicarbonyl compound based on one-pot method of terminal alkyne and acyl halide | 温州大学 | 2020-07-10 | — | — | CN | disclosed |
| CN-110746278-A | Nonmetal-catalyzed method for preparing 1, 3-diketone compound based on alkynone | 四川轻化工大学 | 2020-02-04 | — | — | CN | disclosed |
| CN-105254483-B | A kind of method for preparing the Dicarbonyl derivatives of 2 methyl 1,3 | 苏州大学 | 2017-11-03 | — | — | CN | disclosed |
| CN-105254483-A | Method for preparing 2-methyl-1,3-dicarbonyl derivative | UNIV SOOCHOW | 2016-01-20 | — | — | CN | disclosed |
| EP-0234480-A2 | 1, 3-diketone derivatives and their use | NIHON NOHYAKU CO., LTD. (JP) | 1987-09-02 | — | — | EP | disclosed |