Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLOD2 | O00469 | 1/20 | 0.60 |
| ▸ | NPC1 | O15118 | 2/20 | 0.57 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.57 |
| ▸ | RAB9A | P51151 | 1/20 | 0.57 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.53 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.53 |
| ▸ | HTR7 | P34969 | 1/20 | 0.50 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.50 |
| ▸ | CES2 | O00748 | 1/20 | 0.50 |
| ▸ | CES1 | P23141 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | CA1 | P00915 | 2/20 | 0.46 |
| ▸ | CA2 | P00918 | 2/20 | 0.46 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL3856158 | 0.98 | PLOD2 (0.58) | PLOD2NPC1PTPN1RAB9AMEN1 | |
| SCHEMBL24209439 | 0.89 | PARP10 (0.50) | PLOD2NPC1PTPN1RAB9AMEN1 | |
| SCHEMBL2491432 | 0.86 | PLOD2 (0.69) | PLOD2NPC1PTPN1RAB9AMEN1 | |
| SCHEMBL4720570 | 0.85 | PLOD2 (0.58) | PLOD2NPC1PTPN1RAB9AMEN1 | |
| SCHEMBL30305722 | 0.83 | PLOD2 (0.56) | PLOD2NPC1PTPN1RAB9AMEN1 | |
| SCHEMBL6458755 | 0.81 | NPC1 (0.67) | PLOD2NPC1PTPN1RAB9AMEN1 | |
| SCHEMBL10789236 | 0.80 | TSHR (0.55) | NPC1PTPN1RAB9AMEN1MAPT | |
| SCHEMBL30114978 | 0.80 | PLOD2 (0.62) | PLOD2NPC1PTPN1RAB9AMEN1 | |
| SCHEMBL904555 | 0.80 | PLOD2 (0.62) | PLOD2NPC1PTPN1RAB9AMEN1 | |
| SCHEMBL27745056 | 0.80 | BLM (0.61) | NPC1PTPN1RAB9AMAPTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 34 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113527205-B | Preparation method of blonanserin intermediate | 湖南省湘中制药有限公司 | 2022-04-01 | — | — | CN | claimed |
| CN-110526867-B | Method for efficiently preparing blonanserin intermediate | 湖南省湘中制药有限公司 | 2021-12-03 | — | — | CN | claimed |
| CN-113527205-A | Preparation method of blonanserin intermediate | 湖南省湘中制药有限公司 | 2021-10-22 | — | — | CN | claimed |
| CN-110526867-A | A method of efficiently preparing blonanserin intermediate | HUNAN XIANGZHONG PHARMACEUTICAL CO LTD | 2019-12-03 | — | — | CN | claimed |
| CN-104447551-A | Method for preparing blonanserin | CHEER FINE PHARMACEUTICAL ANHUI CO LTD | 2015-03-25 | — | — | CN | claimed |
| CN-101747273-B | Preparing method of blonanserin intermediate | ZHEJIANG HUAHAI PHARM CO LTD | 2012-03-07 | — | — | CN | claimed |
| CN-102030707-A | Method for preparing Blonanserin intermediate | SHENZHEN WANHE PHARMACEUTICAL CO LTD | 2011-04-27 | — | — | CN | claimed |
| CN-101747273-A | Preparing method of blonanserin intermediate | SHANGHAI INST PHARM INDUSTRY | 2010-06-23 | — | — | CN | claimed |
| CN-119161299-A | Preparation method of anti-schizophrenia drug blonanserin | 湖南大学 | 2024-12-20 | — | — | CN | disclosed |
| CN-119143672-A | Method for synthesizing blonanserin by taking ammonium iodide as nitrogen source | 湖南大学 | 2024-12-17 | — | — | CN | disclosed |
| CN-113527205-B | Preparation method of blonanserin intermediate | 湖南省湘中制药有限公司 | 2022-04-01 | — | — | CN | disclosed |
| CN-113527205-B | Preparation method of blonanserin intermediate | 湖南省湘中制药有限公司 | 2022-04-01 | — | — | CN | disclosed |
| CN-110526867-B | Method for efficiently preparing blonanserin intermediate | 湖南省湘中制药有限公司 | 2021-12-03 | — | — | CN | disclosed |
| CN-110526867-B | Method for efficiently preparing blonanserin intermediate | 湖南省湘中制药有限公司 | 2021-12-03 | — | — | CN | disclosed |
| EP-2048142-A2 | Nitrogen-containing condensed cyclic compound having a pyrazolyl group as a substituent group and pharmaceutical composition thereof | Eisai R&D Management Co., Ltd. (JP) | 2009-04-15 | — | — | EP | disclosed |
| EP-1382603-B1 | NITROGENOUS FUSED-RING COMPOUND HAVING PYRAZOLYL GROUP AS SUBSTITUENT AND MEDICINAL COMPOSITION THEREOF | EISAI R&D MAN CO LTD (JP) | 2008-07-23 | — | — | EP | disclosed |
| US-7217723-B2 | Substituted benzothiophenes, e.g., 7Z)-7-hydroxyimino-4,5,6,7-tetrahydro-benzo[b]thiophene-3-sulfonic acid [2-(4-fluorophenyl)-2-hydroxyethyl]-methyl-amide; treating allergies such as atopic dermatitis, allergic coryza, bronchial asthma, hypersensitive pneumoniac and pulmonary aspergillosis. | EISAI CO., LTD. (JP) | 2007-05-15 | — | — | US | disclosed |
| US-7074801-B1 | Nitrogen-containing condensed cyclic compound having a pyrazolyl group as a substituent group and pharmaceutical composition thereof | EISAI CO., LTD. (JP) | 2006-07-11 | — | — | US | disclosed |
| US-20050227959-A1 | Heterocyclic compound having oxime group | EISAI CO., LTD. (JP) | 2005-10-13 | — | — | US | disclosed |
| EP-1382603-A1 | NITROGENOUS FUSED−RING COMPOUND HAVING PYRAZOLYL GROUP AS SUBSTITUENT AND MEDICINAL COMPOSITION THEREOF | Eisai Co., Ltd. (JP) | 2004-01-21 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050227959-A1 | Heterocyclic compound having oxime group | STAT6, HRH4, HRH2 | PLOD2 4356/4885NPC1 4248/4885PTPN1 454/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.