Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLOD2 | O00469 | 1/20 | 0.62 |
| ▸ | NPC1 | O15118 | 2/20 | 0.59 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.59 |
| ▸ | RAB9A | P51151 | 1/20 | 0.59 |
| ▸ | MAPT | P10636 | 4/20 | 0.55 |
| ▸ | MEN1 | O00255 | 2/20 | 0.55 |
| ▸ | HPGD | P15428 | 2/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.55 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.55 |
| ▸ | HTT | P42858 | 1/20 | 0.55 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.55 |
| ▸ | CES1 | P23141 | 2/20 | 0.52 |
| ▸ | CES2 | O00748 | 1/20 | 0.52 |
| ▸ | HTR7 | P34969 | 1/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.50 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.50 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.50 |
| ▸ | BAD | Q92934 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Fluoride SCHEMBL11175607 | 0.98 | PLOD2 (0.60) | PLOD2NPC1PTPN1RAB9AMAPT | |
| SCHEMBL6824453 | 0.90 | PLOD2 (0.56) | PLOD2NPC1PTPN1RAB9AMAPT | |
| SCHEMBL2491432 | 0.88 | PLOD2 (0.69) | PLOD2NPC1PTPN1RAB9AMAPT | |
| SCHEMBL29249309 | 0.88 | KMT2A (0.62) | PLOD2NPC1PTPN1RAB9AMAPT | |
| SCHEMBL10731900 | 0.84 | MEN1 (0.74) | PLOD2NPC1PTPN1RAB9AMAPT | |
| SCHEMBL13575390 | 0.83 | ERCC5 (0.67) | PLOD2NPC1PTPN1RAB9AMAPT | |
| SCHEMBL11175600 | 0.82 | PLOD2 (0.62) | PLOD2NPC1PTPN1RAB9AMAPT | |
| SCHEMBL30114978 | 0.82 | PLOD2 (0.62) | PLOD2NPC1PTPN1RAB9AMAPT | |
| SCHEMBL9352579 | 0.81 | TSHR (0.60) | NPC1PTPN1RAB9AMAPTMEN1 | |
| SCHEMBL3846985 | 0.80 | PLOD2 (0.60) | PLOD2NPC1PTPN1RAB9AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 64 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101932325-A | Ido inhibitors | NEWLINK GENETICS | 2010-12-29 | — | — | CN | claimed |
| EP-2227233-A2 | IDO INHIBITORS | Newlink Genetics (US) | 2010-09-15 | — | — | EP | claimed |
| WO-2009073620-A2 | IDO INHIBITORS | NEWLINK GENETICS (US) | 2009-06-11 | — | — | WO | claimed |
| CN-118598836-A | Method for asymmetrically synthesizing chiral trans-3, 4-dihydrocoumarin derivative | 中北大学 | 2024-09-06 | — | — | CN | disclosed |
| WO-2024024760-A1 | PYRAZOLONE COMPOUND AND PYRAZOLONE AGENT | 公益財団法人野口研究所 | 2024-02-01 | — | — | WO | disclosed |
| CN-117088861-A | 2-substituted aryl-oxazolin-4-one derivative and application thereof | 浙江大学 | 2023-11-21 | — | — | CN | disclosed |
| CN-113527205-B | Preparation method of blonanserin intermediate | 湖南省湘中制药有限公司 | 2022-04-01 | — | — | CN | disclosed |
| CN-110526867-B | Method for efficiently preparing blonanserin intermediate | 湖南省湘中制药有限公司 | 2021-12-03 | — | — | CN | disclosed |
| CN-113527205-A | Preparation method of blonanserin intermediate | 湖南省湘中制药有限公司 | 2021-10-22 | — | — | CN | disclosed |
| CN-106831603-B | A kind of preparation method containing fluoropyrimidine compound | 辽宁大学 | 2019-07-02 | — | — | CN | disclosed |
| CN-107567442-A | Inhibitors of hepatitis C virus polymerase | 共晶制药公司 | 2018-01-09 | — | — | CN | disclosed |
| US-5124453-A | Treatment of corresponding aldehyde with lithium bis(tri-methylsilyl)amide | E. R. SQUIBB & SONS, INC. (US) | 1992-06-23 | — | — | US | disclosed |
| US-5091378-A | Anticholesterol agents | E. R. SQUIBB & SONS, INC. (US) | 1992-02-25 | — | — | US | disclosed |
| EP-0444532-A1 | Phosphorus-containing HMG-CoA reductase inhibitors, new intermediates and method | E.R. SQUIBB & SONS, INC. (US) | 1991-09-04 | — | — | EP | disclosed |
| US-5025000-A | Anticholesterol, antilipemic agents | E. R. SQUIBB & SONS, INC. (US) | 1991-06-18 | — | — | US | disclosed |
| US-4997837-A | Enzyme inhibitors | WARNER-LAMBERT COMPANY (US) | 1991-03-05 | — | — | US | disclosed |
| US-4906624-A | 6-(((Substituted)pyridin-3-yl)alkyl)-and alkenyl)-tetrahydro-4-hydroxypyran-2-one inhibitors of cholesterol biosynthesis | WARNER-LAMBERT COMPANY (US) | 1990-03-06 | — | — | US | disclosed |
| US-4904671-A | ANTIARTHRITIC AGENTS; PLATELET ACTIVATING FACTOR | PFIZER INC. (US) | 1990-02-27 | — | — | US | disclosed |
| EP-0330327-A2 | Dihydropyridines, their preparation and their use as PAF-antagonists | Pfizer Limited (GB) | 1989-08-30 | — | — | EP | disclosed |
| US-3983239-A | PSYCHOTROPIC | DAINIPPON PHARMACEUTICAL CO., LTD. (JA) | 1976-09-28 | — | — | US | disclosed |