SCHEMBL24914547

SCHEMBL24914547

c1ccc(-c2nc(-c3cccc(-c4cccc5c4oc4ccccc45)c3)nc(-n3c4ccccc4c4ccc5c(c6ccccc6n5-c5ccccc5)c43)n2)cc1

nearest known ligand 0.38

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 2/20 0.38
PRKDC P78527 3/20 0.34
GGPS1 O95749 1/20 0.34
KDM4E B2RXH2 1/20 0.32
ATM Q13315 1/20 0.32
L3MBTL1 Q9Y468 1/20 0.32
PTGES2 Q9H7Z7 1/20 0.32
TSHR P16473 1/20 0.31
MAPT P10636 1/20 0.31
PIK3CD O00329 1/20 0.31
PIK3CB P42338 1/20 0.31
PRMT5 O14744 1/20 0.31
WDR77 Q9BQA1 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22049944 0.96 ALOX5 (0.38) ALOX5PRKDCGGPS1PTGES2TSHR
SCHEMBL12691273 0.95 ALOX5 (0.38) ALOX5PRKDCGGPS1KDM4EATM
SCHEMBL19769872 0.94 KDM4E (0.34) ALOX5PRKDCKDM4EATML3MBTL1
SCHEMBL25965188 0.93 PRKDC (0.34) ALOX5PRKDCKDM4EATML3MBTL1
SCHEMBL19769875 0.92 ALOX5 (0.34) ALOX5PRKDCKDM4EATML3MBTL1
SCHEMBL24914572 0.92 KDM4E (0.34) KDM4EATML3MBTL1
SCHEMBL22050441 0.92 ALOX5 (0.41) ALOX5PRKDCGGPS1KDM4EATM
SCHEMBL22049194 0.92 ALOX5 (0.41) ALOX5PRKDCGGPS1KDM4EATM
SCHEMBL16451996 0.91 ALOX5 (0.32) ALOX5
SCHEMBL23602250 0.90 ALOX5 (0.33) ALOX5PRKDCKDM4ETSHRMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230157165-A1 ORGANIC ELECTROLUMINESCENT COMPOUND, A PLURALITY OF HOST MATERIALS AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME ROHM AND HAAS ELECTRONIC MATERIALS KOREA LTD. (KR) 2023-05-18 US disclosed
US-20230157165-A1 ORGANIC ELECTROLUMINESCENT COMPOUND, A PLURALITY OF HOST MATERIALS AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME ROHM AND HAAS ELECTRONIC MATERIALS KOREA LTD. (KR) 2023-05-18 US disclosed
US-20230019297-A1 PLURALITY OF HOST MATERIALS AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME DUPONT SPECIALTY MATERIALS KOREA LTD. (KR) 2023-01-19 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230157165-A1 ORGANIC ELECTROLUMINESCENT COMPOUND, A PLURALITY OF HOST MATERIALS AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME L1CAM, MCM2, MAL2 ALOX5 676/4885PRKDC 3009/4885GGPS1 466/4885
US-20230019297-A1 PLURALITY OF HOST MATERIALS AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME TERT, TELO2, SOD1 ALOX5 503/4885PRKDC 3902/4885GGPS1 399/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.