SCHEMBL24914852

SCHEMBL24914852

C=CCN(C(=O)c1ccc(F)cc1)c1cccc(C(=O)Nc2c(I)cc(C(P)(C(F)(F)F)C(F)(F)F)cc2C(F)(F)F)c1F

nearest known ligand 0.32

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
CTSS P25774 1/20 0.32
KCNJ11 Q14654 1/20 0.30
CA12 O43570 1/20 0.30
CA9 Q16790 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24914763 0.87 KCNK3 (0.35) CTSSKCNJ11
SCHEMBL24914954 0.84 RXFP1 (0.37) CTSSKCNJ11
SCHEMBL24914495 0.83 PTGES (0.31) CTSS
SCHEMBL24914632 0.82 PTGES (0.30) CTSS
SCHEMBL20846767 0.82 CTSS (0.36) CTSSCA12CA9
SCHEMBL24914856 0.81
SCHEMBL24914543 0.80 BCHE (0.32)
SCHEMBL24914857 0.80 BRAF (0.33)
SCHEMBL24914948 0.80 KCNK3 (0.34) CTSSKCNJ11
SCHEMBL24914487 0.80 POLQ (0.34) CTSSCA12CA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023284645-A1 AMIDE COMPOUND AND USE THEREOF 沈阳化工大学 2023-01-19 WO disclosed