Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | ATAD2 | Q6PL18 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | XBP1 | P17861 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.41 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.40 |
| ▸ | LCK | P06239 | 1/20 | 0.39 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.39 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15858102 | 0.89 | KDM4E (0.61) | KDM4EHSD17B10MAPTLMNAALDH1A1 | |
| SCHEMBL7383587 | 0.89 | KDM4E (0.57) | KDM4EHSD17B10MAPTLMNAALDH1A1 | |
| SCHEMBL8149013 | 0.87 | MAP4K4 (0.41) | MAPTMEN1KMT2AMAP4K4HDAC3 | |
| SCHEMBL10305747 | 0.86 | MAP4K4 (0.46) | ALDH1A1MAP4K4HDAC3HDAC1HDAC2 | |
| Hydrochloric Acid SCHEMBL7387616 | 0.86 | MAP4K4 (0.39) | KDM4EHSD17B10MAP4K4HDAC3HDAC1 | |
| SCHEMBL19426643 | 0.84 | KDM4E (0.39) | KDM4EHSD17B10MAPTLMNAATAD2 | |
| SCHEMBL31568470 | 0.84 | KDM4E (0.55) | KDM4EHSD17B10MAPTLMNAALDH1A1 | |
| SCHEMBL26032283 | 0.84 | CA12 (0.56) | KDM4EHSD17B10MAPTLMNAALDH1A1 | |
| SCHEMBL9396335 | 0.84 | KDM4E (0.55) | KDM4EHSD17B10MAPTLMNAALDH1A1 | |
| SCHEMBL22469882 | 0.84 | KDM4E (0.55) | KDM4EHSD17B10MAPTLMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230133581-A1 | Novel 3,5-Diaminobenzoic Acid Compound, and PIN1 Inhibitor and Therapeutic Agent for Inflammatory Diseases Using Same | HIROSHIMA UNIVERSITY (JP) | 2023-05-04 | — | — | US | disclosed |
| US-20230133581-A1 | Novel 3,5-Diaminobenzoic Acid Compound, and PIN1 Inhibitor and Therapeutic Agent for Inflammatory Diseases Using Same | HIROSHIMA UNIVERSITY (JP) | 2023-05-04 | — | — | US | disclosed |
| EP-4119165-A1 | NOVEL 3,5-DIAMINOBENZOIC ACID COMPOUND, AND PIN1 INHIBITOR AND THERAPEUTIC AGENT FOR INFLAMMATORY DISEASES USING SAME | Hiroshima University (JP) | 2023-01-18 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230133581-A1 | Novel 3,5-Diaminobenzoic Acid Compound, and PIN1 Inhibitor and Therapeutic Agent for Inflammatory Diseases Using Same | PIN1, DUSP15, FKBP1A | KDM4E 3752/4885HSD17B10 281/4885MAPT 574/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.