Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CXCR4 | P61073 | 2/20 | 0.68 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.49 |
| ▸ | CYP2A13 | Q16696 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | JAK2 | O60674 | 1/20 | 0.39 |
| ▸ | JAK3 | P52333 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | NCF1 | P14598 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24915182 | 0.86 | CXCR4 (0.48) | CXCR4ALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL946951 | 0.85 | CXCR4 (0.47) | CXCR4SMN1; SMN2ALDH1A1KMT2AKCNH2 | |
| SCHEMBL29604383 | 0.82 | CXCR4 (1.00) | CXCR4ALOX15CYP2A13SMN1; SMN2ALDH1A1 | |
| SCHEMBL6479913 | 0.81 | PDE10A (0.49) | CXCR4 | |
| Hydrochloric Acid SCHEMBL29604752 | 0.81 | CXCR4 (0.96) | CXCR4ALOX15CYP2A13SMN1; SMN2ALDH1A1 | |
| Bromide SCHEMBL29604076 | 0.81 | CXCR4 (0.96) | CXCR4ALOX15CYP2A13SMN1; SMN2ALDH1A1 | |
| SCHEMBL13273494 | 0.78 | CXCR4 (0.83) | CXCR4ALOX15CYP2A13SMN1; SMN2ALDH1A1 | |
| SCHEMBL947570 | 0.77 | FKBP1A (0.48) | SMN1; SMN2ALDH1A1KDM4EHTT | |
| SCHEMBL4547964 | 0.75 | CXCR4 (0.77) | CXCR4ALOX15CYP2A13SMN1; SMN2ALDH1A1 | |
| SCHEMBL22304486 | 0.75 | CXCR4 (0.83) | CXCR4ALOX15CYP2A13SMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230145793-A1 | SUBSTITUTED PYRIMIDINE OR PYRIDINE AMINE DERIVATIVE, COMPOSITION THEREOF, AND MEDICAL USE THEREOF | SHANGHAI HAIYAN PHARMACEUTICAL TECHNOLOGY CO., LTD. (CN) | 2023-05-11 | — | — | US | disclosed |
| US-20230145793-A1 | SUBSTITUTED PYRIMIDINE OR PYRIDINE AMINE DERIVATIVE, COMPOSITION THEREOF, AND MEDICAL USE THEREOF | SHANGHAI HAIYAN PHARMACEUTICAL TECHNOLOGY CO., LTD. (CN) | 2023-05-11 | — | — | US | disclosed |
| EP-4122927-A1 | SUBSTITUTED PYRIMIDINE OR PYRIDINE AMINE DERIVATIVE, COMPOSITION THEREOF, AND MEDICAL USE THEREOF | Shanghai Haiyan Pharmaceutical Technology Co., Ltd. (CN) | 2023-01-25 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230145793-A1 | SUBSTITUTED PYRIMIDINE OR PYRIDINE AMINE DERIVATIVE, COMPOSITION THEREOF, AND MEDICAL USE THEREOF | ADORA2A, ADORA2B, ADORA3 | CXCR4 611/4885ALOX15 1208/4885CYP2A13 203/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.