Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE2A | O00408 | 6/20 | 0.38 |
| ▸ | PDE10A | Q9Y233 | 5/20 | 0.36 |
| ▸ | PDE6D | O43924 | 3/20 | 0.36 |
| ▸ | PDE6A | P16499 | 3/20 | 0.36 |
| ▸ | PDE6G | P18545 | 3/20 | 0.36 |
| ▸ | PDE6B | P35913 | 3/20 | 0.36 |
| ▸ | PDE6C | P51160 | 3/20 | 0.36 |
| ▸ | PDE6H | Q13956 | 3/20 | 0.36 |
| ▸ | PDE5A | O76074 | 1/20 | 0.36 |
| ▸ | TLR9 | Q9NR96 | 2/20 | 0.35 |
| ▸ | TLR8 | Q9NR97 | 2/20 | 0.35 |
| ▸ | TLR7 | Q9NYK1 | 2/20 | 0.35 |
| ▸ | F2RL3 | Q96RI0 | 2/20 | 0.34 |
| ▸ | NPY1R | P25929 | 2/20 | 0.33 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.32 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.32 |
| ▸ | PDE1A | P54750 | 1/20 | 0.32 |
| ▸ | PDE1B | Q01064 | 1/20 | 0.32 |
| ▸ | PDE1C | Q14123 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24916405 | 0.76 | HPGD (0.43) | PDE10A | |
| SCHEMBL24915974 | 0.74 | KMT2A (0.40) | PDE10A | |
| SCHEMBL24915688 | 0.71 | MAPK14 (0.36) | PDE10AF2RL3 | |
| SCHEMBL28716824 | 0.70 | TSHR (0.50) | — | |
| SCHEMBL29560183 | 0.70 | TSHR (0.50) | — | |
| SCHEMBL24916057 | 0.70 | HTR1A (0.43) | — | |
| SCHEMBL24916052 | 0.69 | P2RX3 (0.37) | NPY1R | |
| SCHEMBL24916058 | 0.69 | KDM4E (0.50) | — | |
| SCHEMBL24915923 | 0.68 | CD38 (0.45) | — | |
| SCHEMBL24916054 | 0.68 | HTR1B (0.41) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230026466-A1 | WDR5 INHIBITORS AND MODULATORS | VANDERBILT UNIVERSITY | 2023-01-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230026466-A1 | WDR5 INHIBITORS AND MODULATORS | WDR5, WDR1, WDR3 | PDE2A 4070/4885PDE10A 3835/4885PDE6D 4318/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.