Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.40 |
| ▸ | PDE10A | Q9Y233 | 4/20 | 0.40 |
| ▸ | POLB | P06746 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | RAD52 | P43351 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | GAA | P10253 | 3/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.39 |
| ▸ | JAK2 | O60674 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | P2RX3 | P56373 | 3/20 | 0.37 |
| ▸ | P2RX2 | Q9UBL9 | 3/20 | 0.37 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.37 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.37 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.36 |
| ▸ | CRHR1 | P34998 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24916053 | 0.81 | DHFR (0.43) | POLBGAAMAPTP2RX3P2RX2 | |
| SCHEMBL20867656 | 0.80 | MAPT (0.50) | KMT2APOLBSMN1; SMN2LMNARAD52 | |
| SCHEMBL24916052 | 0.80 | P2RX3 (0.37) | KMT2APOLBMEN1GAAMAPT | |
| SCHEMBL24916058 | 0.79 | KDM4E (0.50) | POLBSMN1; SMN2LMNACYP1A2GAA | |
| SCHEMBL20867783 | 0.78 | GFER (0.48) | PDE10APOLBSMN1; SMN2LMNAGAA | |
| SCHEMBL20521940 | 0.78 | KMT2A (0.44) | KMT2APDE10APOLBSMN1; SMN2LMNA | |
| SCHEMBL20521814 | 0.78 | CYP3A4 (0.44) | KMT2APOLBSMN1; SMN2LMNARAD52 | |
| SCHEMBL22750299 | 0.78 | CRHR1 (0.47) | KMT2APOLBSMN1; SMN2LMNARAD52 | |
| SCHEMBL29923906 | 0.78 | CRHR1 (0.47) | KMT2APOLBSMN1; SMN2LMNARAD52 | |
| SCHEMBL24915923 | 0.77 | CD38 (0.45) | POLBSMN1; SMN2P2RX3P2RX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230026466-A1 | WDR5 INHIBITORS AND MODULATORS | VANDERBILT UNIVERSITY | 2023-01-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230026466-A1 | WDR5 INHIBITORS AND MODULATORS | WDR5, WDR1, WDR3 | KMT2A 641/4885PDE10A 3835/4885POLB 3227/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.