SCHEMBL2494964

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2491447	0.91	KIF11 (0.40)	ALDH1A1HSD17B10CA1CA2CA12
	SCHEMBL2491593	0.90	CA1 (0.41)	ALDH1A1HSD17B10CA1CA2CA12
	SCHEMBL15841458	0.85	ALDH1A1 (0.42)	ALDH1A1HSD17B10KDM4ESMN1; SMN2L3MBTL1
	SCHEMBL1260567	0.85	ALDH1A1 (0.42)	ALDH1A1HSD17B10KDM4ESMN1; SMN2L3MBTL1
	SCHEMBL2493848	0.83	TAAR1 (0.43)	ALDH1A1CA1CA2CA12CA4
	SCHEMBL2494552	0.81	KIF11 (0.42)	ALDH1A1HSD17B10CA1CA2CA12
	SCHEMBL992027	0.81	KIF11 (0.42)	ALDH1A1HSD17B10CA1CA2CA12
	SCHEMBL2491343	0.79	ALDH1A1 (0.36)	ALDH1A1KDM4ETSHRCTNNB1WNT3A
	SCHEMBL2490799	0.79	KIF11 (0.52)	ALDH1A1CA1CA2CA12CA4
	SCHEMBL2492368	0.77	ALDH1A1 (0.41)	ALDH1A1HSD17B10CA2CA12CA4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.