Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | LRRK2 | Q5S007 | 2/20 | 0.40 |
| ▸ | ELANE | P08246 | 1/20 | 0.39 |
| ▸ | GSK3B | P49841 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.37 |
| ▸ | TP53 | P04637 | 3/20 | 0.37 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | PDE1B | Q01064 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24916357 | 0.90 | MAPT (0.47) | MAPTSMN1; SMN2GAAALDH1A1KDM4E | |
| SCHEMBL24915841 | 0.87 | KDM4E (0.44) | MAPTSMN1; SMN2GAAALDH1A1KDM4E | |
| SCHEMBL24916132 | 0.85 | KDM4E (0.42) | MAPTSMN1; SMN2GAAALDH1A1LRRK2 | |
| SCHEMBL24916359 | 0.85 | HTT (0.46) | MAPTSMN1; SMN2ALDH1A1KDM4ETP53 | |
| SCHEMBL24915840 | 0.83 | MTNR1B (0.46) | MAPTSMN1; SMN2ALDH1A1LRRK2KDM4E | |
| SCHEMBL24916363 | 0.83 | ALDH1A1 (0.39) | MAPTSMN1; SMN2GAAALDH1A1GSK3B | |
| SCHEMBL24915839 | 0.82 | LRRK2 (0.39) | MAPTSMN1; SMN2GAAALDH1A1LRRK2 | |
| SCHEMBL24916364 | 0.81 | TLR9 (0.41) | MAPTSMN1; SMN2ALDH1A1LRRK2ELANE | |
| SCHEMBL24916360 | 0.78 | KDM4E (0.43) | MAPTSMN1; SMN2GAAALDH1A1KDM4E | |
| SCHEMBL24916365 | 0.78 | NSD2 (0.39) | MAPTSMN1; SMN2GAAKDM4ETP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230026466-A1 | WDR5 INHIBITORS AND MODULATORS | VANDERBILT UNIVERSITY | 2023-01-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230026466-A1 | WDR5 INHIBITORS AND MODULATORS | WDR5, WDR1, WDR3 | MAPT 1413/4885SMN1; SMN2 2582/4885GAA 3980/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.