Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS2 | P35228 | 3/20 | 0.32 |
| ▸ | NOS1 | P29475 | 2/20 | 0.32 |
| ▸ | NOS3 | P29474 | 1/20 | 0.32 |
| ▸ | ARG1 | P05089 | 1/20 | 0.32 |
| ▸ | ARG2 | P78540 | 1/20 | 0.32 |
| ▸ | METAP1 | P53582 | 1/20 | 0.31 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4167234 | 0.78 | ALDH1A1 (0.42) | ARG1ARG2 | |
| SCHEMBL4167228 | 0.78 | ALDH1A1 (0.42) | ARG1ARG2 | |
| SCHEMBL2633077 | 0.77 | DPP7 (0.36) | METAP1DPP7 | |
| SCHEMBL2739489 | 0.77 | DPP7 (0.36) | METAP1DPP7 | |
| SCHEMBL1274426 | 0.77 | CA12 (0.35) | METAP1DPP7 | |
| SCHEMBL2189880 | 0.77 | CA12 (0.35) | METAP1DPP7 | |
| SCHEMBL24311695 | 0.77 | METAP1 (0.32) | METAP1 | |
| SCHEMBL21955443 | 0.76 | ARG1 (0.36) | NOS2NOS1NOS3ARG1ARG2 | |
| SCHEMBL24013206 | 0.76 | FCER2 (0.40) | — | |
| SCHEMBL21553675 | 0.75 | MAPT (0.36) | METAP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230183292-A1 | IMMUNOMODULATORS | BRISTOL MYERS SQUIBB CO (US) | 2023-06-15 | — | — | US | disclosed |
| WO-2023004240-A1 | MACROCYLIC IMMUNOMODULATORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2023-01-26 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230183292-A1 | IMMUNOMODULATORS | CD274, PDCD1LG2, PDCD1 | NOS2 1554/4885NOS1 1721/4885NOS3 2201/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.