Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS3 | P29474 | 1/20 | 0.36 |
| ▸ | NOS1 | P29475 | 1/20 | 0.36 |
| ▸ | NOS2 | P35228 | 1/20 | 0.36 |
| ▸ | HTR1A | P08908 | 1/20 | 0.32 |
| ▸ | HTR1D | P28221 | 1/20 | 0.32 |
| ▸ | HTR1B | P28222 | 1/20 | 0.32 |
| ▸ | LOXL2 | Q9Y4K0 | 2/20 | 0.32 |
| ▸ | LOX | P28300 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24916036 | 0.83 | KDM4E (0.36) | NOS3NOS1NOS2 | |
| SCHEMBL24916205 | 0.83 | SLC6A2 (0.36) | NOS3NOS1NOS2 | |
| SCHEMBL24915675 | 0.82 | LOXL2 (0.33) | NOS3NOS1NOS2LOXL2LOX | |
| SCHEMBL22253420 | 0.79 | NPC1 (0.36) | NOS3NOS1NOS2HTR1A | |
| SCHEMBL24916037 | 0.79 | KMT2A (0.32) | — | |
| SCHEMBL24916206 | 0.78 | L3MBTL1 (0.45) | — | |
| SCHEMBL24916204 | 0.77 | MEN1 (0.32) | — | |
| SCHEMBL24915647 | 0.77 | NOS3 (0.33) | NOS3NOS1NOS2 | |
| SCHEMBL24916426 | 0.76 | HPGD (0.35) | NOS3NOS1NOS2 | |
| SCHEMBL24916411 | 0.75 | ACE2 (0.40) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230026466-A1 | WDR5 INHIBITORS AND MODULATORS | VANDERBILT UNIVERSITY | 2023-01-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230026466-A1 | WDR5 INHIBITORS AND MODULATORS | WDR5, WDR1, WDR3 | NOS3 4274/4885NOS1 4026/4885NOS2 4252/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.