Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATP4A | P20648 | 2/20 | 0.43 |
| ▸ | ATP4B | P51164 | 2/20 | 0.43 |
| ▸ | P2RX3 | P56373 | 7/20 | 0.40 |
| ▸ | P2RX2 | Q9UBL9 | 7/20 | 0.40 |
| ▸ | CCR1 | P32246 | 1/20 | 0.38 |
| ▸ | CCR5 | P51681 | 1/20 | 0.38 |
| ▸ | CCR8 | P51685 | 1/20 | 0.38 |
| ▸ | HPGDS | O60760 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | CNR2 | P34972 | 1/20 | 0.36 |
| ▸ | ACHE | P22303 | 1/20 | 0.35 |
| ▸ | TNF | P01375 | 1/20 | 0.35 |
| ▸ | LITAF | Q99732 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24916307 | 0.80 | CCR1 (0.42) | ATP4AATP4BCCR1CCR5CCR8 | |
| SCHEMBL24915646 | 0.78 | P2RX3 (0.37) | ATP4AATP4BP2RX3P2RX2MEN1 | |
| SCHEMBL24715886 | 0.78 | NQO2 (0.47) | CCR1CCR5CCR8HPGDSLMNA | |
| SCHEMBL29923737 | 0.78 | CCR1 (0.40) | ATP4AATP4BCCR1CCR5CCR8 | |
| SCHEMBL24916302 | 0.78 | CCR1 (0.40) | ATP4AATP4BCCR1CCR5CCR8 | |
| SCHEMBL24715864 | 0.78 | MAPT (0.44) | ATP4AATP4BCCR1CCR5CCR8 | |
| SCHEMBL24715871 | 0.78 | CCR1 (0.40) | ATP4AATP4BCCR1CCR5CCR8 | |
| SCHEMBL24762553 | 0.78 | CCR1 (0.40) | P2RX3P2RX2CCR1CCR5CCR8 | |
| SCHEMBL24634726 | 0.74 | GAA (0.51) | ATP4AATP4BMEN1KMT2A | |
| SCHEMBL24915600 | 0.72 | P2RX3 (0.40) | ATP4AATP4BP2RX3P2RX2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230026466-A1 | WDR5 INHIBITORS AND MODULATORS | VANDERBILT UNIVERSITY | 2023-01-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230026466-A1 | WDR5 INHIBITORS AND MODULATORS | WDR5, WDR1, WDR3 | ATP4A 3440/4885ATP4B 3081/4885P2RX3 3671/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.