Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX3 | P56373 | 3/20 | 0.40 |
| ▸ | P2RX2 | Q9UBL9 | 3/20 | 0.40 |
| ▸ | GPR55 | Q9Y2T6 | 2/20 | 0.39 |
| ▸ | CNR2 | P34972 | 2/20 | 0.36 |
| ▸ | ATP4A | P20648 | 2/20 | 0.35 |
| ▸ | ATP4B | P51164 | 2/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.34 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.34 |
| ▸ | NSD2 | O96028 | 1/20 | 0.34 |
| ▸ | CASP6 | P55212 | 1/20 | 0.34 |
| ▸ | TNKS | O95271 | 1/20 | 0.33 |
| ▸ | GPR18 | Q14330 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24915645 | 0.78 | NSD2 (0.44) | P2RX3P2RX2NSD2CASP6 | |
| SCHEMBL29923591 | 0.78 | NQO2 (0.37) | TNKSMEN1KMT2AMAPT | |
| SCHEMBL24916494 | 0.78 | NQO2 (0.37) | TNKSMEN1KMT2AMAPT | |
| SCHEMBL21783731 | 0.73 | MTNR1B (0.47) | RECQLMEN1KMT2AHSD17B10 | |
| SCHEMBL24916213 | 0.72 | ATP4A (0.43) | P2RX3P2RX2CNR2ATP4AATP4B | |
| SCHEMBL24842479 | 0.71 | P2RX3 (0.40) | P2RX3P2RX2RECQLMEN1ALDH1A1 | |
| SCHEMBL19297226 | 0.70 | GPR55 (0.36) | GPR55ATP4AATP4BMEN1KMT2A | |
| SCHEMBL26400677 | 0.70 | MET (0.43) | P2RX3P2RX2 | |
| SCHEMBL24915594 | 0.70 | MTNR1B (0.33) | P2RX3P2RX2MEN1ALDH1A1ALOX15 | |
| SCHEMBL24916219 | 0.69 | PDE10A (0.41) | P2RX3P2RX2NSD2CASP6MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230026466-A1 | WDR5 INHIBITORS AND MODULATORS | VANDERBILT UNIVERSITY | 2023-01-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230026466-A1 | WDR5 INHIBITORS AND MODULATORS | WDR5, WDR1, WDR3 | P2RX3 3671/4885P2RX2 3727/4885GPR55 1904/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.