Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 1/20 | 0.34 |
| ▸ | HTR4 | Q13639 | 3/20 | 0.33 |
| ▸ | SLC2A1 | P11166 | 2/20 | 0.33 |
| ▸ | MTNR1A | P48039 | 4/20 | 0.32 |
| ▸ | MTNR1B | P49286 | 4/20 | 0.32 |
| ▸ | TLR8 | Q9NR97 | 2/20 | 0.31 |
| ▸ | TLR7 | Q9NYK1 | 2/20 | 0.31 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.31 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.31 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24916523 | 0.78 | SMYD3 (0.34) | CNR2TLR8TLR7TLR9 | |
| SCHEMBL24916014 | 0.74 | MAP4K4 (0.36) | TLR8TLR7TLR9 | |
| SCHEMBL24916238 | 0.73 | FGFR3 (0.32) | — | |
| SCHEMBL24916217 | 0.73 | CALM1 (0.33) | TLR7 | |
| SCHEMBL24916369 | 0.73 | MAP4K4 (0.39) | HTR4SLC2A1 | |
| SCHEMBL24915855 | 0.72 | ALDH1A1 (0.45) | MTNR1AMTNR1B | |
| SCHEMBL24915850 | 0.72 | KDM4E (0.47) | CNR2 | |
| SCHEMBL24915856 | 0.71 | JAK2 (0.42) | — | |
| SCHEMBL24915854 | 0.71 | MTNR1A (0.43) | MTNR1A | |
| SCHEMBL24915998 | 0.70 | SMYD3 (0.47) | CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230026466-A1 | WDR5 INHIBITORS AND MODULATORS | VANDERBILT UNIVERSITY | 2023-01-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230026466-A1 | WDR5 INHIBITORS AND MODULATORS | WDR5, WDR1, WDR3 | CNR2 3646/4885HTR4 4061/4885SLC2A1 3666/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.