Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DYRK1A | Q13627 | 2/20 | 0.41 |
| ▸ | P2RX3 | P56373 | 2/20 | 0.41 |
| ▸ | P2RX2 | Q9UBL9 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | CYP17A1 | P05093 | 3/20 | 0.38 |
| ▸ | CYP11B1 | P15538 | 3/20 | 0.38 |
| ▸ | CYP11B2 | P19099 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | DYRK3 | O43781 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24916401 | 0.82 | P2RX3 (0.42) | DYRK1AP2RX3P2RX2KDM4EALDH1A1 | |
| SCHEMBL24916397 | 0.82 | P2RX3 (0.42) | DYRK1AP2RX3P2RX2KDM4EALDH1A1 | |
| SCHEMBL1536440 | 0.81 | PLAU (0.46) | DYRK1AKDM4EALDH1A1LMNAHPGD | |
| SCHEMBL13729538 | 0.80 | DYRK1A (0.43) | DYRK1AKDM4EALDH1A1LMNAHPGD | |
| SCHEMBL10304674 | 0.80 | DYRK1A (0.43) | DYRK1AKDM4EALDH1A1LMNAHPGD | |
| SCHEMBL1536565 | 0.80 | DYRK1A (0.43) | DYRK1AKDM4EALDH1A1LMNAHPGD | |
| SCHEMBL15685810 | 0.79 | DYRK1A (0.42) | DYRK1AKDM4EALDH1A1LMNAHPGD | |
| SCHEMBL15647724 | 0.79 | ALDH1A1 (0.44) | DYRK1AKDM4EALDH1A1LMNAHPGD | |
| SCHEMBL13728895 | 0.79 | DYRK1A (0.42) | DYRK1AKDM4EALDH1A1LMNAHPGD | |
| SCHEMBL13728377 | 0.79 | DYRK1A (0.42) | DYRK1AKDM4EALDH1A1LMNAHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230026466-A1 | WDR5 INHIBITORS AND MODULATORS | VANDERBILT UNIVERSITY | 2023-01-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230026466-A1 | WDR5 INHIBITORS AND MODULATORS | WDR5, WDR1, WDR3 | DYRK1A 2337/4885P2RX3 3671/4885P2RX2 3727/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.