Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | PARP15 | Q460N3 | 1/20 | 0.41 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.41 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.41 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.40 |
| ▸ | MMP2 | P08253 | 4/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.40 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
| ▸ | MMP3 | P08254 | 2/20 | 0.39 |
| ▸ | ESR1 | P03372 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24916671 | 0.78 | GAA (0.40) | GAAKMT2AKDM4EMAPTALDH1A1 | |
| SCHEMBL10971280 | 0.73 | PARP15 (0.56) | GAAKMT2AKDM4EMAPTALDH1A1 | |
| SCHEMBL10154344 | 0.72 | KMT2A (0.60) | GAAKMT2AKDM4EMAPTALDH1A1 | |
| SCHEMBL2163526 | 0.70 | L3MBTL1 (0.57) | GAAKMT2AKDM4EMAPTALDH1A1 | |
| SCHEMBL3372818 | 0.69 | MAPT (0.62) | GAAKMT2AKDM4EMAPTALDH1A1 | |
| SCHEMBL4770909 | 0.69 | ALDH1A1 (0.53) | GAAKMT2AKDM4EMAPTALDH1A1 | |
| SCHEMBL2835052 | 0.69 | GAA (0.60) | GAAKMT2AKDM4EMAPTALDH1A1 | |
| SCHEMBL17615977 | 0.68 | MMP2 (0.51) | KDM4EMAPTALDH1A1MMP2POLB | |
| SCHEMBL14548246 | 0.68 | MMP2 (0.51) | KDM4EMAPTALDH1A1MMP2POLB | |
| SCHEMBL8190496 | 0.68 | ALDH1A1 (0.44) | GAAKMT2AKDM4EMAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023288033-A1 | ASGPR CELL SURFACE RECEPTOR BINDING COMPOUNDS AND CONJUGATES | LYCIA THERAPEUTICS, INC. (US) | 2023-01-19 | — | — | WO | disclosed |