Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLRMT | O00411 | 1/20 | 0.33 |
| ▸ | TMPRSS2 | O15393 | 1/20 | 0.32 |
| ▸ | DGAT1 | O75907 | 6/20 | 0.32 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.30 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.30 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.30 |
| ▸ | DOT1L | Q8TEK3 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25913427 | 0.97 | POLRMT (0.31) | POLRMTTMPRSS2DGAT1 | |
| SCHEMBL24790438 | 0.96 | POLRMT (0.32) | POLRMTTMPRSS2 | |
| SCHEMBL25913274 | 0.96 | POLRMT (0.32) | POLRMTTMPRSS2 | |
| SCHEMBL24790453 | 0.96 | POLRMT (0.32) | POLRMTTMPRSS2 | |
| SCHEMBL24789844 | 0.96 | POLRMT (0.32) | POLRMTTMPRSS2 | |
| SCHEMBL25913344 | 0.95 | ACVRL1 (0.33) | POLRMTTMPRSS2 | |
| SCHEMBL24916890 | 0.95 | TMPRSS2 (0.32) | POLRMTTMPRSS2DGAT1CSNK2A2CSNK2A1 | |
| SCHEMBL24917618 | 0.94 | DGAT1 (0.30) | DGAT1 | |
| SCHEMBL25913295 | 0.93 | RIPK1 (0.36) | POLRMTTMPRSS2 | |
| SCHEMBL25913447 | 0.93 | PIK3CD (0.32) | POLRMTTMPRSS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230233593-A1 | ORALLY-BIOAVAILABLE NUCLEOSIDE ANALOGS | VenatoRx Pharmaceuticals, Inc. | 2023-07-27 | — | — | US | disclosed |
| US-11638715-B2 | Orally-bioavailable nucleoside analogs | VenatoRx Pharmaceuticals, Inc. (US) | 2023-05-02 | — | — | US | disclosed |
| US-20230024722-A1 | ORALLY-BIOAVAILABLE NUCLEOSIDE ANALOGS | VenatoRx Pharmaceuticals, Inc. | 2023-01-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230024722-A1 | ORALLY-BIOAVAILABLE NUCLEOSIDE ANALOGS | SLC29A2, SLC29A1, PNP | POLRMT 138/4885TMPRSS2 100/4885DGAT1 538/4885 |
| US-11638715-B2 | Orally-bioavailable nucleoside analogs | SLC29A2, SLC29A1, PNP | POLRMT 138/4885TMPRSS2 100/4885DGAT1 538/4885 |
| US-20230233593-A1 | ORALLY-BIOAVAILABLE NUCLEOSIDE ANALOGS | SLC29A2, SLC29A1, PNP | POLRMT 138/4885TMPRSS2 100/4885DGAT1 538/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.