Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGLN2 | Q96KS0 | 2/20 | 0.30 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.30 |
| ▸ | DOT1L | Q8TEK3 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24917868 | 0.91 | CTSS (0.31) | — | |
| SCHEMBL24916982 | 0.91 | CTSS (0.31) | — | |
| SCHEMBL24916983 | 0.90 | EGLN2 (0.33) | EGLN2AAK1DOT1L | |
| SCHEMBL24916997 | 0.90 | EGLN2 (0.33) | EGLN2AAK1DOT1L | |
| SCHEMBL24917023 | 0.88 | CTSL (0.31) | — | |
| SCHEMBL25924977 | 0.84 | TMPRSS2 (0.37) | — | |
| SCHEMBL24917009 | 0.83 | EGLN2 (0.30) | EGLN2 | |
| SCHEMBL24917352 | 0.83 | EGLN2 (0.30) | EGLN2 | |
| SCHEMBL24917245 | 0.82 | CTSK (0.31) | — | |
| SCHEMBL24917053 | 0.81 | REN (0.38) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230024722-A1 | ORALLY-BIOAVAILABLE NUCLEOSIDE ANALOGS | VenatoRx Pharmaceuticals, Inc. | 2023-01-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230024722-A1 | ORALLY-BIOAVAILABLE NUCLEOSIDE ANALOGS | SLC29A2, SLC29A1, PNP | EGLN2 2347/4885AAK1 3585/4885DOT1L 3715/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.