Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDGFRB | P09619 | 1/20 | 0.42 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.42 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.42 |
| ▸ | FLT1 | P17948 | 1/20 | 0.42 |
| ▸ | FGFR3 | P22607 | 1/20 | 0.42 |
| ▸ | KDR | P35968 | 1/20 | 0.42 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.40 |
| ▸ | GLA | P06280 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 4/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.37 |
| ▸ | NPC1 | O15118 | 3/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7098144 | 0.93 | PDGFRB (0.46) | PDGFRBFGFR1PDGFRAFLT1FGFR3 | |
| SCHEMBL769393 | 0.85 | PDGFRB (0.50) | PDGFRBFGFR1PDGFRAFLT1FGFR3 | |
| SCHEMBL249897 | 0.85 | PDGFRB (0.40) | PDGFRBFGFR1PDGFRAFLT1FGFR3 | |
| SCHEMBL27176850 | 0.83 | EGFR (0.43) | PDGFRBFGFR1PDGFRAFLT1FGFR3 | |
| SCHEMBL5485173 | 0.81 | PDGFRB (0.43) | PDGFRBFGFR1PDGFRAFLT1FGFR3 | |
| SCHEMBL31701357 | 0.81 | PDGFRB (0.43) | PDGFRBFGFR1PDGFRAFLT1FGFR3 | |
| SCHEMBL29946112 | 0.81 | PDGFRB (0.43) | PDGFRBFGFR1PDGFRAFLT1FGFR3 | |
| SCHEMBL22830400 | 0.81 | PDGFRB (0.43) | PDGFRBFGFR1PDGFRAFLT1FGFR3 | |
| SCHEMBL27176767 | 0.81 | MTNR1A (0.46) | PDGFRBFGFR1PDGFRAFLT1FGFR3 | |
| SCHEMBL26036108 | 0.79 | PDGFRB (0.40) | PDGFRBFGFR1PDGFRAFLT1FGFR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2352375-B1 | HERBICIDAL COMPOSITIONS | SYNGENTA PARTICIPATIONS AG (CH) | 2015-03-25 | — | — | EP | disclosed |
| US-8722578-B2 | Spiroheterocyclic pyrrolidinedione herbicidal compositions | SYNGENTA PARTICIPATIONS AG (CH) | 2014-05-13 | — | — | US | disclosed |
| EP-2421865-B1 | SPIROHETEROCYCLIC PYRROLIDINE DIONE DERIVATIVES USED AS PESTICIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2013-07-10 | — | — | EP | disclosed |
| US-8415369-B2 | Spiroheterocyclic pyrrolidine dione derivatives useful as pesticides | SYNGENTA CROP PROTECTION LLC (US) | 2013-04-09 | — | — | US | disclosed |
| EP-2197844-B1 | SPIROHETEROCYCLIC PYRROLIDINE DIONE DERIVATIVES USEFUL AS PESTICIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2012-07-25 | — | — | EP | disclosed |
| EP-2421865-A1 | SPIROHETEROCYCLIC PYRROLIDINE DIONE DERIVATIVES USED AS PESTICIDES | Syngenta Participations AG (CH) | 2012-02-29 | — | — | EP | disclosed |
| US-20120035201-A1 | SPIROHETEROCYCLIC PYRROLIDINE DIONE DERIVATIVES USED AS PESTICIDES | SYNGENTA CROP PROTECTION LLC (US) | 2012-02-09 | — | — | US | disclosed |
| US-20120004105-A1 | HERBICIDAL COMPOSITIONS | SYNGENTA CROP PROTECTION LLC (US) | 2012-01-05 | — | — | US | disclosed |
| CN-102209469-A | Herbicidal compositions | SYNGENTA PARTICIPATIONS AG | 2011-10-05 | — | — | CN | disclosed |
| EP-2352375-A2 | HERBICIDAL COMPOSITIONS | Syngenta Participations AG (CH) | 2011-08-10 | — | — | EP | disclosed |
| US-20100311777-A1 | SPIROHETEROCYCLIC PYRROLIDINE DIONE DERIVATIVES USEFUL AS PESTICIDES | SYNGENTA CROP PROTECTION, INC. (US) | 2010-12-09 | — | — | US | disclosed |
| WO-2010115780-A1 | SPIROHETEROCYCLIC PYRROLIDINE DIONE DERIVATIVES USED AS PESTICIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2010-10-14 | — | — | WO | disclosed |
| EP-2197844-A1 | SPIROHETEROCYCLIC PYRROLIDINE DIONE DERIVATIVES USEFUL AS PESTICIDES | Syngeta Participations AG (CH) | 2010-06-23 | — | — | EP | disclosed |
| WO-2010052161-A2 | HERBICIDAL COMPOSITIONS | SYNGENTA PARTICIPATIONS AG (CH) | 2010-05-14 | — | — | WO | disclosed |
| WO-2009049851-A1 | SPIROHETEROCYCLIC PYRROLIDINE DIONE DERIVATIVES USEFUL AS PESTICIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2009-04-23 | — | — | WO | disclosed |
| US-6806264-B2 | PESTICIDES AND HERBICIDES; WOOD PROTECTANTS | BAYER AKTIENGESELLSCHAFT (DE) | 2004-10-19 | — | — | US | disclosed |
| US-20040127365-A1 | Arylphenyl-substituted cyclic ketoenols | LIEB FOLKER (DE) | 2004-07-01 | — | — | US | disclosed |
| US-6693092-B2 | HERBICIDES; PESTICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 2004-02-17 | — | — | US | disclosed |
| US-20030073851-A1 | Arylphenyl-substituted cyclic ketoenols | LIEB FOLKER (DE) | 2003-04-17 | — | — | US | disclosed |
| US-6458965-B1 | HERBICIDES, ANTIGROWTH AGENTS AND SURFACTANTS FOR WOOD PRESERVATIVES | BAYER AKTIENGESELLSCHAFT (DE) | 2002-10-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120004105-A1 | HERBICIDAL COMPOSITIONS | DDT, CAT, HDHD5 | PDGFRB 2976/4885FGFR1 1752/4885PDGFRA 3315/4885 |
| US-20030073851-A1 | Arylphenyl-substituted cyclic ketoenols | KCNE1, CYP2E1, CYP21A2 | PDGFRB 3193/4885FGFR1 2826/4885PDGFRA 2775/4885 |
| US-20100311777-A1 | SPIROHETEROCYCLIC PYRROLIDINE DIONE DERIVATIVES USEFUL AS PESTICIDES | DDT, PKD2, PKD1 | PDGFRB 3974/4885FGFR1 2909/4885PDGFRA 2967/4885 |
| US-20120035201-A1 | SPIROHETEROCYCLIC PYRROLIDINE DIONE DERIVATIVES USED AS PESTICIDES | DDT, PKD2, PKD1 | PDGFRB 4309/4885FGFR1 2976/4885PDGFRA 3760/4885 |
| US-20040127365-A1 | Arylphenyl-substituted cyclic ketoenols | KCNE1, CYP2E1, CYP21A2 | PDGFRB 3193/4885FGFR1 2826/4885PDGFRA 2775/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.