SCHEMBL24919609

SCHEMBL24919609

CC(C)Cc1ncc(Cl)cc1F

nearest known ligand 0.33

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CRHR1 P34998 2/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
S1PR1 P21453 3/20 0.32
S1PR3 Q99500 3/20 0.32
LTA4H P09960 1/20 0.32
KCNH2 Q12809 1/20 0.32
TRPM5 Q9NZQ8 1/20 0.31
MAPK1 P28482 1/20 0.31
PDE3B Q13370 1/20 0.31
PDE3A Q14432 1/20 0.31
PDE10A Q9Y233 1/20 0.31
TRPV3 Q8NET8 1/20 0.31
BDKRB1 P46663 1/20 0.31
KDM4E B2RXH2 2/20 0.30
TSHR P16473 1/20 0.30
P2RX3 P56373 1/20 0.30
P2RX2 Q9UBL9 1/20 0.30
MET P08581 1/20 0.30
TGFBR1 P36897 1/20 0.30
USP2 O75604 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17000219 0.81 AGBL2 (0.40) KDM4EUSP2HPGDHSD17B10
SCHEMBL23998926 0.81 CRHR1 (0.37) CRHR1SMN1; SMN2MAPK1PDE3BPDE3A
SCHEMBL10272604 0.79 CRHR1 (0.38) CRHR1S1PR1S1PR3TRPM5MAPK1
SCHEMBL23346613 0.76 CRHR1 (0.35) CRHR1S1PR1S1PR3MAPK1PDE3B
SCHEMBL10235257 0.76 S1PR1 (0.32) SMN1; SMN2S1PR1S1PR3LTA4HKCNH2
SCHEMBL25023639 0.75 S1PR1 (0.34) S1PR1S1PR3LTA4HKCNH2TRPM5
SCHEMBL6866870 0.75 PRMT5 (0.36) S1PR1S1PR3LTA4HKCNH2TRPM5
SCHEMBL9952921 0.75 PLAU (0.36) S1PR1S1PR3LTA4HKCNH2TRPM5
Hydrochloric Acid SCHEMBL9953137 0.75 S1PR1 (0.31) S1PR1S1PR3LTA4HKCNH2TRPM5
SCHEMBL22912583 0.74 KLKB1 (0.41) LTA4HKCNH2TRPM5MAPK1P2RX3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230212140-A1 GLP-1 RECEPTOR AGONIST AND USE THEREOF ILDONG PHARMACEUTICAL CO., LTD. (KR) 2023-07-06 US disclosed
US-11643403-B2 GLP-1 receptor agonist and use thereof ILDONG PHARMACEUTICAL CO., LTD. (KR) 2023-05-09 US disclosed
US-20230013143-A1 GLP-1 RECEPTOR AGONIST AND USE THEREOF ILDONG PHARMACEUTICAL CO., LTD. (KR) 2023-01-19 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230013143-A1 GLP-1 RECEPTOR AGONIST AND USE THEREOF GLP1R, GIPR, GPR119 CRHR1 97/4885SMN1; SMN2 2779/4885S1PR1 596/4885
US-20230212140-A1 GLP-1 RECEPTOR AGONIST AND USE THEREOF GLP1R, GIPR, GPR119 CRHR1 97/4885SMN1; SMN2 2779/4885S1PR1 596/4885
US-11643403-B2 GLP-1 receptor agonist and use thereof GLP1R, GIPR, GPR119 CRHR1 97/4885SMN1; SMN2 2779/4885S1PR1 596/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.