Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SNCA | P37840 | 1/20 | 0.36 |
| ▸ | IDO1 | P14902 | 1/20 | 0.34 |
| ▸ | TDO2 | P48775 | 1/20 | 0.34 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.34 |
| ▸ | PDGFRB | P09619 | 2/20 | 0.33 |
| ▸ | KDR | P35968 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24920074 | 0.79 | IDO1 (0.34) | SNCAIDO1TDO2IRAK4 | |
| SCHEMBL24919875 | 0.76 | SNCA (0.51) | SNCA | |
| SCHEMBL29786772 | 0.69 | LPL (0.46) | SNCA | |
| SCHEMBL8749259 | 0.69 | LPL (0.46) | SNCA | |
| SCHEMBL24920100 | 0.68 | SNCA (0.33) | SNCA | |
| SCHEMBL24920105 | 0.68 | PRMT5 (0.34) | IDO1TDO2 | |
| SCHEMBL24920098 | 0.68 | IRAK4 (0.33) | IRAK4 | |
| SCHEMBL29915023 | 0.67 | CYP2A6 (0.40) | SNCAIRAK4 | |
| SCHEMBL27002489 | 0.67 | CYP2A6 (0.40) | SNCAIRAK4 | |
| SCHEMBL32664206 | 0.66 | HIF1A (0.38) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023004138-A1 | AGONISTS OF TYRO3 AS PROTECTION AGAINST PODOCYTE INJURY IN KIDNEY GLOMERULAR DISEASE | DAS BHASKAR (US) | 2023-01-26 | — | — | WO | disclosed |