Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 1/20 | 0.34 |
| ▸ | TDO2 | P48775 | 1/20 | 0.34 |
| ▸ | SNCA | P37840 | 1/20 | 0.33 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.32 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24920073 | 0.79 | SNCA (0.36) | IDO1TDO2SNCAIRAK4 | |
| SCHEMBL24919875 | 0.75 | SNCA (0.51) | SNCAMEN1KMT2A | |
| SCHEMBL11000 | 0.73 | ATM (0.41) | IRAK4PRMT5WDR77 | |
| SCHEMBL24920106 | 0.71 | PRMT5 (0.36) | IDO1TDO2PRMT5WDR77 | |
| SCHEMBL24920098 | 0.70 | IRAK4 (0.33) | IRAK4MEN1KMT2A | |
| SCHEMBL31468044 | 0.69 | LPL (0.45) | IDO1TDO2PRMT5WDR77 | |
| SCHEMBL30665809 | 0.69 | LPL (0.39) | PRMT5WDR77 | |
| SCHEMBL30665811 | 0.69 | LPL (0.39) | PRMT5WDR77 | |
| SCHEMBL30742479 | 0.69 | CYP1A2 (0.40) | MEN1KMT2APRMT5WDR77 | |
| SCHEMBL26879745 | 0.69 | CYP1A2 (0.40) | MEN1KMT2APRMT5WDR77 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023004138-A1 | AGONISTS OF TYRO3 AS PROTECTION AGAINST PODOCYTE INJURY IN KIDNEY GLOMERULAR DISEASE | DAS BHASKAR (US) | 2023-01-26 | — | — | WO | disclosed |