Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 2/20 | 0.54 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.54 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | HPGD | P15428 | 2/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.50 |
| ▸ | HTR1A | P08908 | 1/20 | 0.50 |
| ▸ | HTR2C | P28335 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 3/20 | 0.48 |
| ▸ | CA12 | O43570 | 2/20 | 0.43 |
| ▸ | CA1 | P00915 | 2/20 | 0.43 |
| ▸ | CA2 | P00918 | 2/20 | 0.43 |
| ▸ | CA4 | P22748 | 2/20 | 0.43 |
| ▸ | CA6 | P23280 | 2/20 | 0.43 |
| ▸ | CA5A | P35218 | 2/20 | 0.43 |
| ▸ | CA7 | P43166 | 2/20 | 0.43 |
| ▸ | CA9 | Q16790 | 2/20 | 0.43 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.43 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28630448 | 0.84 | PKM (0.61) | PKMPTGS1PTGS2KDM4EALDH1A1 | |
| SCHEMBL9101731 | 0.82 | PKM (0.55) | PKMPTGS1PTGS2KDM4EALDH1A1 | |
| SCHEMBL976533 | 0.81 | PKM (0.58) | PKMPTGS1PTGS2KDM4EALDH1A1 | |
| SCHEMBL16093497 | 0.79 | NFE2L2 (0.62) | PKMPTGS1PTGS2KDM4EALDH1A1 | |
| SCHEMBL2394283 | 0.78 | PKM (0.54) | PKMPTGS1PTGS2KDM4EALDH1A1 | |
| SCHEMBL3789794 | 0.77 | KDM4E (0.65) | PKMPTGS1PTGS2KDM4EALDH1A1 | |
| SCHEMBL3789790 | 0.77 | KDM4E (0.65) | PKMPTGS1PTGS2KDM4EALDH1A1 | |
| SCHEMBL25380226 | 0.77 | KDM4E (0.60) | PKMPTGS1PTGS2KDM4EALDH1A1 | |
| SCHEMBL6852555 | 0.75 | NFE2L2 (0.69) | PKMPTGS1PTGS2KDM4EALDH1A1 | |
| SCHEMBL6852559 | 0.75 | NFE2L2 (0.69) | PKMPTGS1PTGS2KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8580775-B2 | Use of derivatives of sinapinic acid and compositions comprising such derivatives | COGNIS IP MANAGEMENT GMBH (DE) | 2013-11-12 | — | — | US | disclosed |
| EP-2117499-B1 | Use of sinapic acid in non-therapeutic cosmetic and/or topical compositions | COGNIS IP MAN GMBH (DE) | 2011-10-26 | — | — | EP | disclosed |
| US-20100130605-A1 | Use of Derivatives of Sinapinic Acid and Compositions Comprising Such Derivatives | COGNIS IP MANAGEMENT GMBH (DE) | 2010-05-27 | — | — | US | disclosed |
| EP-2117499-A1 | USE OF DERIVATIVES OF SINAPINIC ACID AND COMPOSITIONS COMPRISING SUCH DERIVATIVES | Cognis IP Management GmbH (DE) | 2009-11-18 | — | — | EP | disclosed |
| WO-2008107093-A1 | USE OF DERIVATIVES OF SINAPINIC ACID AND COMPOSITIONS COMPRISING SUCH DERIVATIVES | COGNIS IP MANAGEMENT GMBH (DE) | 2008-09-12 | — | — | WO | disclosed |
| EP-1967175-A1 | Use of derivatives of sinapinic acid and compositions comprising such derivatives | Cognis IP Management GmbH (DE) | 2008-09-10 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100130605-A1 | Use of Derivatives of Sinapinic Acid and Compositions Comprising Such Derivatives | TYR, ASAH1, AANAT | PKM 1859/4885PTGS1 449/4885PTGS2 895/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.