SCHEMBL976533

SCHEMBL976533

COc1cc(C=CC(=O)O)c(C)c(OC)c1O

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PKM P14618 3/20 0.58
PTGS1 P23219 1/20 0.58
PTGS2 P35354 1/20 0.58
KDM4E B2RXH2 6/20 0.54
ALDH1A1 P00352 4/20 0.54
HPGD P15428 2/20 0.54
HSD17B10 Q99714 2/20 0.54
HTR1A P08908 1/20 0.54
HTR2C P28335 1/20 0.54
GAA P10253 2/20 0.51
SMN1; SMN2 Q16637 3/20 0.50
CA12 O43570 3/20 0.47
CA1 P00915 3/20 0.47
CA2 P00918 3/20 0.47
CA4 P22748 3/20 0.47
CA6 P23280 3/20 0.47
CA5A P35218 3/20 0.47
CA7 P43166 3/20 0.47
CA9 Q16790 3/20 0.47
CA14 Q9ULX7 3/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28630448 0.91 PKM (0.61) PKMPTGS1PTGS2KDM4EALDH1A1
SCHEMBL19328293 0.88 KDM4E (0.61) PKMPTGS1PTGS2KDM4EALDH1A1
SCHEMBL27391381 0.84 NPC1 (0.60) ALDH1A1SMN1; SMN2SNCAABCG2
SCHEMBL27391382 0.84 NPC1 (0.60) ALDH1A1SMN1; SMN2SNCAABCG2
SCHEMBL9101731 0.82 PKM (0.55) PKMPTGS1PTGS2KDM4EALDH1A1
SCHEMBL2492020 0.81 PKM (0.54) PKMPTGS1PTGS2KDM4EALDH1A1
SCHEMBL2394283 0.81 PKM (0.54) PKMPTGS1PTGS2KDM4EALDH1A1
SCHEMBL16385977 0.80 NFE2L2 (0.62) PKMPTGS1PTGS2KDM4EALDH1A1
SCHEMBL6852559 0.78 NFE2L2 (0.69) PKMPTGS1PTGS2KDM4EALDH1A1
SCHEMBL6852555 0.78 NFE2L2 (0.69) PKMPTGS1PTGS2KDM4EALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7163673-B2 Sunscreen reagents from hydroxy-substituted acylglycerides THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF AGRICULTURE (US) 2007-01-16 US claimed
US-20040258743-A1 Novel sunscreen reagents from hydroxy-substituted acylglycerides AGRICULTURE, THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF 2004-12-23 US claimed
WO-2022145167-A1 ORAL COMPOSITION ライオン株式会社 2022-07-07 WO disclosed
WO-2022102465-A1 ALDEHYDE COMPOSITION 三菱瓦斯化学株式会社 2022-05-19 WO disclosed
WO-2022085670-A1 ALICYCLIC ALCOHOL, ALICYCLIC ALCOHOL COMPOSITION, AND PERFUME COMPOSITION 三菱瓦斯化学株式会社 2022-04-28 WO disclosed
EP-3592341-B1 TOPICAL COMPOSITIONS CONTAINING SYNTHETIC ESTERS OF SINAPINIC ACID AND METHODS FOR TREATING KERATIN SURFACES ELC MAN LLC (US) 2021-12-01 EP disclosed
US-7875262-B2 Oil in water emulsion of droplets of a cinnamate-modified vegetable oil distributed in a continuous aqueous starch solution in the absence of an external emulsifier; delivery system for ultra violet-protective sunscreen agents, antioxidants, skin care agents, cosmetics; lower concentration of oil needed THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF AGRICULTURE (US) 2011-01-25 US disclosed
US-7351403-B2 Sunscreen reagents from unsaturated waxes and triglycerides THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF AGRICULTURE (US) 2008-04-01 US disclosed
WO-2007076432-A2 AQUEOUS STARCH-OIL DISPERSIONS HAVING IMPROVED UV STABILITY AND ABSORBING ABILITY THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF AGRICULTURE (US) 2007-07-05 WO disclosed
US-20070140995-A1 Aqueous starch-oil dispersions having improved UV stability and absorbing ability THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF AGRICULTURE (US) 2007-06-21 US disclosed
US-7163673-B2 Sunscreen reagents from hydroxy-substituted acylglycerides THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF AGRICULTURE (US) 2007-01-16 US disclosed
US-7087671-B2 Recycled plastic molded parts for photosensitive materials FUJI PHOTO FILM CO., LTD. (JP) 2006-08-08 US disclosed
WO-2005065637-A1 NOVEL SUSNSCREEN REAGENTS FROM HYDROXY-SUBSTITUTED ACYLGLYCERIDES THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF AGRICULTURE (US) 2005-07-21 WO disclosed
US-20040258635-A1 Novel sunscreen reagents from unsaturated waxes and triglycerides AGRICULTURE, UNITED STATES OF AMERICA, THE, AS REPRESENTED BY THE SECREATARY OF 2004-12-23 US disclosed
US-20040258743-A1 Novel sunscreen reagents from hydroxy-substituted acylglycerides AGRICULTURE, THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF 2004-12-23 US disclosed
US-6783715-B2 CRUSHING; PELLETIZATION; USING AS MOLDING MATERIALS FUJI PHOTO FILM CO., LTD. (JP) 2004-08-31 US disclosed
US-20040092612-A1 Method of recycling mold plastic parts for photosensitive material and a recycled plastic mold parts FUJI PHOTO FILM CO., LTD. (JP) 2004-05-13 US disclosed
US-20020038921-A1 Method of recycling mold plastic parts for photosensitive material and a recycled plastic mold parts FUJI PHOTO FILM CO., LTD. 2002-04-04 US disclosed
EP-1193039-A1 Method of recycling plastic parts for photosensitive material FUJI PHOTO FILM CO., LTD. (JP) 2002-04-03 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070140995-A1 Aqueous starch-oil dispersions having improved UV stability and absorbing ability LIPG, MAFG, FRG1 PKM 2245/4885PTGS1 2541/4885PTGS2 1960/4885
US-20040258743-A1 Novel sunscreen reagents from hydroxy-substituted acylglycerides FADS1, LIPA, LIPC PKM 3258/4885PTGS1 1863/4885PTGS2 1392/4885
US-20040258635-A1 Novel sunscreen reagents from unsaturated waxes and triglycerides TTPA, LRAT, CUTA PKM 4714/4885PTGS1 3036/4885PTGS2 2466/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.