Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GNAO1 | P09471 | 3/20 | 0.41 |
| ▸ | GNAI3 | P08754 | 2/20 | 0.41 |
| ▸ | GNAI1 | P63096 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | PAOX | Q6QHF9 | 1/20 | 0.39 |
| ▸ | HRH3 | Q9Y5N1 | 4/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20234238 | 0.85 | ALDH1A1 (0.50) | ALDH1A1USP2HPGDPAOXHRH3 | |
| SCHEMBL20231214 | 0.85 | ALDH1A1 (0.50) | ALDH1A1USP2HPGDPAOXHRH3 | |
| SCHEMBL23158354 | 0.85 | ALDH1A1 (0.50) | ALDH1A1USP2HPGDPAOXHRH3 | |
| SCHEMBL24920949 | 0.85 | ALDH1A1 (0.50) | ALDH1A1USP2HPGDPAOXHRH3 | |
| SCHEMBL24921700 | 0.84 | HRH1 (0.38) | HRH3MEN1 | |
| SCHEMBL24920416 | 0.83 | ALDH1A1 (0.46) | GNAO1GNAI3GNAI1ALDH1A1USP2 | |
| SCHEMBL10305196 | 0.83 | ALDH1A1 (0.51) | ALDH1A1USP2HPGDPAOXHRH3 | |
| SCHEMBL24307348 | 0.82 | NCF1 (0.41) | ALDH1A1HPGDHRH3KDM4E | |
| SCHEMBL24920445 | 0.81 | HTR2A (0.35) | HRH3KDM4E | |
| SCHEMBL24921696 | 0.80 | ALDH1A1 (0.44) | GNAO1GNAI3GNAI1ALDH1A1USP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023006097-A1 | BIFUNCTIONAL CHIMERIC HETEROCYCLIC COMPOUND AND USE THEREOF AS ANDROGEN RECEPTOR DEGRADER | 海创药业股份有限公司 | 2023-02-02 | — | — | WO | disclosed |