Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 1/20 | 0.35 |
| ▸ | HTR2C | P28335 | 1/20 | 0.35 |
| ▸ | HTR2B | P41595 | 1/20 | 0.35 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | HRH1 | P35367 | 2/20 | 0.33 |
| ▸ | HRH2 | P25021 | 1/20 | 0.33 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24920448 | 0.81 | GNAO1 (0.41) | KDM4EHRH3 | |
| SCHEMBL24920959 | 0.80 | SIGMAR1 (0.42) | SIGMAR1 | |
| SCHEMBL24920453 | 0.80 | SIGMAR1 (0.42) | SIGMAR1 | |
| SCHEMBL24921844 | 0.79 | NCF1 (0.38) | HTR2AHTR2CHTR2BSIGMAR1KDM4E | |
| SCHEMBL4401614 | 0.77 | CHRM5 (0.48) | SIGMAR1 | |
| SCHEMBL24307348 | 0.75 | NCF1 (0.41) | KDM4EHRH1HRH2HRH3 | |
| SCHEMBL27370590 | 0.74 | ALDH1A1 (0.44) | KDM4EMAPTHRH3 | |
| SCHEMBL20234243 | 0.74 | ALDH1A1 (0.45) | SIGMAR1KDM4EMAPTHRH3 | |
| SCHEMBL27267687 | 0.74 | NCF1 (0.43) | HTR2AHTR2CHTR2BSIGMAR1KDM4E | |
| SCHEMBL24920407 | 0.73 | ALDH1A1 (0.42) | KDM4EMAPTHRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023006097-A1 | BIFUNCTIONAL CHIMERIC HETEROCYCLIC COMPOUND AND USE THEREOF AS ANDROGEN RECEPTOR DEGRADER | 海创药业股份有限公司 | 2023-02-02 | — | — | WO | disclosed |