Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DYRK1A | Q13627 | 2/20 | 0.38 |
| ▸ | TTK | P33981 | 1/20 | 0.37 |
| ▸ | PDCD1LG2 | Q9BQ51 | 1/20 | 0.36 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.36 |
| ▸ | HPGD | P15428 | 4/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | RXRA | P19793 | 5/20 | 0.34 |
| ▸ | GRIN1 | Q05586 | 5/20 | 0.34 |
| ▸ | GRIN2B | Q13224 | 5/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24920538 | 0.91 | DYRK1A (0.44) | DYRK1AHSD17B10ALDH1A1CYP3A4USP2 | |
| SCHEMBL24920525 | 0.88 | DYRK1A (0.52) | DYRK1ATTKHSD17B10CYP3A4CYP2D6 | |
| SCHEMBL24920536 | 0.82 | ACHE (0.48) | ALDH1A1HPGDCYP3A4CYP2D6LMNA | |
| SCHEMBL24920534 | 0.81 | HSD17B10 (0.45) | HSD17B10ALDH1A1HPGDCYP3A4USP2 | |
| SCHEMBL24921025 | 0.81 | RXRA (0.39) | DYRK1AAOC3RXRAGRIN1GRIN2B | |
| SCHEMBL24921032 | 0.80 | AOC3 (0.39) | DYRK1AAOC3RXRAGRIN1GRIN2B | |
| SCHEMBL24920516 | 0.80 | HSD17B10 (0.41) | DYRK1AHSD17B10ALDH1A1HPGDCYP3A4 | |
| SCHEMBL24920535 | 0.78 | SLC6A2 (0.40) | ALDH1A1HPGDHTTL3MBTL1AOC3 | |
| SCHEMBL24921023 | 0.76 | AOC3 (0.44) | DYRK1AAOC3RXRAGRIN1GRIN2B | |
| SCHEMBL24921040 | 0.76 | AOC3 (0.44) | DYRK1AHTTAOC3RXRAGRIN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023006097-A1 | BIFUNCTIONAL CHIMERIC HETEROCYCLIC COMPOUND AND USE THEREOF AS ANDROGEN RECEPTOR DEGRADER | 海创药业股份有限公司 | 2023-02-02 | — | — | WO | disclosed |