Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 3/20 | 0.48 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.48 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.48 |
| ▸ | PIK3R1 | P27986 | 1/20 | 0.48 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.48 |
| ▸ | MTOR | P42345 | 5/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | EIF2AK2 | P19525 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | CA12 | O43570 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | CA9 | Q16790 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24921023 | 0.88 | AOC3 (0.44) | ACHEKDM4EKMT2ACA12CA1 | |
| SCHEMBL24921040 | 0.88 | AOC3 (0.44) | ACHEMEN1KMT2ACA12CA1 | |
| SCHEMBL24920520 | 0.86 | MAPT (0.46) | ACHEMEN1HPGDKMT2ACA12 | |
| SCHEMBL24920548 | 0.85 | ACHE (0.48) | ACHEALDH1A1MEN1KMT2ACA12 | |
| SCHEMBL24920535 | 0.84 | SLC6A2 (0.40) | ACHEPIK3CAPIK3CDPIK3R1PIK3CB | |
| SCHEMBL24920523 | 0.84 | ADRB1 (0.51) | ACHEALDH1A1KDM4EHPGDCYP1A2 | |
| SCHEMBL17827961 | 0.83 | PIK3CA (0.51) | ACHEPIK3CAPIK3CDPIK3R1PIK3CB | |
| SCHEMBL24920567 | 0.82 | DYRK1A (0.38) | ACHEALDH1A1L3MBTL1HPGDCA12 | |
| SCHEMBL20745766 | 0.82 | CA12 (0.47) | ACHEPIK3CAPIK3CDPIK3R1PIK3CB | |
| SCHEMBL24920538 | 0.82 | DYRK1A (0.44) | ALDH1A1L3MBTL1CYP3A4CYP2D6LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023006097-A1 | BIFUNCTIONAL CHIMERIC HETEROCYCLIC COMPOUND AND USE THEREOF AS ANDROGEN RECEPTOR DEGRADER | 海创药业股份有限公司 | 2023-02-02 | — | — | WO | disclosed |