Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPBWR1 | P48145 | 3/20 | 0.37 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.37 |
| ▸ | FGFR2 | P21802 | 1/20 | 0.34 |
| ▸ | LTA4H | P09960 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 3/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.32 |
| ▸ | LCK | P06239 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24922128 | 0.82 | KMT2A (0.52) | NPBWR1MEN1KMT2AEGLN1ALDH1A1 | |
| SCHEMBL24920613 | 0.82 | ACACB (0.37) | MEN1KMT2AALDH1A1SCN9AHPGD | |
| SCHEMBL20912238 | 0.81 | EGLN1 (0.39) | MEN1KMT2AEGLN1ALDH1A1HCRTR1 | |
| SCHEMBL24921249 | 0.80 | ACACB (0.31) | ALDH1A1SCN9ANPC1RAB9AHPGD | |
| SCHEMBL27233964 | 0.80 | ACACB (0.31) | ALDH1A1SCN9ANPC1RAB9AHPGD | |
| SCHEMBL27233960 | 0.80 | ACACB (0.31) | ALDH1A1SCN9ANPC1RAB9AHPGD | |
| SCHEMBL24922127 | 0.76 | LTA4H (0.39) | NPBWR1MCHR1FGFR2LTA4HMEN1 | |
| SCHEMBL30399915 | 0.75 | LTA4H (0.56) | LTA4HMEN1KMT2AALDH1A1NPC1 | |
| SCHEMBL25986532 | 0.75 | LTA4H (0.56) | LTA4HMEN1KMT2AALDH1A1NPC1 | |
| SCHEMBL30212243 | 0.74 | NPBWR1 (0.38) | NPBWR1MCHR1FGFR2EGLN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023006097-A1 | BIFUNCTIONAL CHIMERIC HETEROCYCLIC COMPOUND AND USE THEREOF AS ANDROGEN RECEPTOR DEGRADER | 海创药业股份有限公司 | 2023-02-02 | — | — | WO | disclosed |