Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 9/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.36 |
| ▸ | PIM1 | P11309 | 1/20 | 0.35 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | CCR1 | P32246 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14031549 | 0.78 | PDPK1 (0.40) | MAPTPDPK1CYP1A2CYP3A4CYP2C19 | |
| SCHEMBL24921146 | 0.77 | CCR1 (0.59) | NOTUMALDH1A1HPGDMAPK1MAPT | |
| SCHEMBL24920893 | 0.74 | PTGDR (0.45) | NOTUMALDH1A1PDPK1KMT2APIM1 | |
| SCHEMBL24921973 | 0.73 | MAPT (0.42) | NOTUMALDH1A1HPGDMAPK1MAPT | |
| SCHEMBL24921176 | 0.72 | NOTUM (0.54) | NOTUMALDH1A1HPGDMAPK1MAPT | |
| SCHEMBL24920898 | 0.72 | PDPK1 (0.39) | HPGDMAPTPDPK1CYP1A2CYP3A4 | |
| SCHEMBL24920787 | 0.71 | ALDH1A1 (0.43) | NOTUMALDH1A1HPGDMAPK1MAPT | |
| SCHEMBL14031547 | 0.71 | PTGDR (0.45) | NOTUMPDPK1CYP3A4GAA | |
| SCHEMBL24920894 | 0.71 | ACHE (0.40) | HPGDMAPTPDPK1CYP2C19HSD17B10 | |
| SCHEMBL15921756 | 0.70 | KDM4E (0.53) | ALDH1A1HPGDMAPK1MAPTPDPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023006097-A1 | BIFUNCTIONAL CHIMERIC HETEROCYCLIC COMPOUND AND USE THEREOF AS ANDROGEN RECEPTOR DEGRADER | 海创药业股份有限公司 | 2023-02-02 | — | — | WO | disclosed |