Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 5/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.34 |
| ▸ | EGFR | P00533 | 1/20 | 0.34 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.34 |
| ▸ | RET | P07949 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24921515 | 0.75 | HSD17B10 (0.40) | L3MBTL1MAPTHSD17B10KDM4EGAA | |
| SCHEMBL24921157 | 0.75 | L3MBTL1 (0.50) | L3MBTL1MAPTHSD17B10KDM4EGAA | |
| SCHEMBL24920903 | 0.74 | CNR2 (0.40) | MAPTHSD17B10NPSR1HPGDNPC1 | |
| SCHEMBL24921482 | 0.73 | MAPT (0.48) | L3MBTL1MAPTHSD17B10KDM4EGAA | |
| SCHEMBL24920822 | 0.73 | KMO (0.48) | MAPTKDM4ENPC1RAB9ASMN1; SMN2 | |
| SCHEMBL24921145 | 0.73 | CCR1 (0.58) | L3MBTL1MAPTHSD17B10KDM4EGAA | |
| SCHEMBL14667327 | 0.73 | L3MBTL1 (0.56) | L3MBTL1MAPTHSD17B10KDM4EGAA | |
| SCHEMBL16481894 | 0.73 | S1PR1 (0.64) | L3MBTL1MAPTNPC1SMN1; SMN2S1PR1 | |
| SCHEMBL16583245 | 0.73 | MAPT (0.47) | L3MBTL1MAPTHSD17B10KDM4EGAA | |
| SCHEMBL24920769 | 0.72 | MAPT (0.40) | L3MBTL1MAPTHSD17B10KDM4EGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023006097-A1 | BIFUNCTIONAL CHIMERIC HETEROCYCLIC COMPOUND AND USE THEREOF AS ANDROGEN RECEPTOR DEGRADER | 海创药业股份有限公司 | 2023-02-02 | — | — | WO | disclosed |