Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 2/20 | 0.40 |
| ▸ | ACHE | P22303 | 2/20 | 0.37 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.36 |
| ▸ | BCHE | P06276 | 1/20 | 0.35 |
| ▸ | LRRK2 | Q5S007 | 2/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.33 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.33 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 3/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17109493 | 0.75 | BTK (0.42) | ACHESMN1; SMN2MAPTNPC1RAB9A | |
| SCHEMBL24921488 | 0.75 | CNR2 (0.41) | CNR2ACHES1PR1CYP2C19BCHE | |
| SCHEMBL14031556 | 0.75 | CYP2C19 (0.38) | CYP2C19MAPTNPC1RAB9ACYP2C9 | |
| SCHEMBL24920820 | 0.75 | CYP2C19 (0.38) | CYP2C19SMN1; SMN2MAPTNPC1RAB9A | |
| SCHEMBL24920871 | 0.74 | L3MBTL1 (0.41) | S1PR1CYP2C19HTTCHEK1SMN1; SMN2 | |
| SCHEMBL24921491 | 0.73 | ACHE (0.42) | CNR2ACHECYP2C19BCHEHTT | |
| SCHEMBL24921187 | 0.73 | S1PR1 (0.64) | ACHES1PR1BCHEHTTSMN1; SMN2 | |
| SCHEMBL17109385 | 0.73 | CCR1 (0.58) | CNR2ACHECYP2C19SMN1; SMN2MAPT | |
| SCHEMBL23997060 | 0.73 | CNR2 (0.51) | CNR2ACHES1PR1BCHELRRK2 | |
| SCHEMBL24920887 | 0.72 | CYP11B2 (0.38) | CNR2ACHES1PR1CYP2C19BCHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023006097-A1 | BIFUNCTIONAL CHIMERIC HETEROCYCLIC COMPOUND AND USE THEREOF AS ANDROGEN RECEPTOR DEGRADER | 海创药业股份有限公司 | 2023-02-02 | — | — | WO | disclosed |