Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDO2 | P48775 | 1/20 | 0.36 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.33 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.33 |
| ▸ | EGLN1 | Q9GZT9 | 3/20 | 0.32 |
| ▸ | ALKBH1 | Q13686 | 1/20 | 0.32 |
| ▸ | GRM5 | P41594 | 2/20 | 0.32 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.31 |
| ▸ | RXRA | P19793 | 2/20 | 0.31 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.31 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24921233 | 0.78 | CCR1 (0.44) | EGLN1GRM5MAPT | |
| SCHEMBL24920821 | 0.73 | KDM4E (0.43) | TDO2MAPT | |
| SCHEMBL24921150 | 0.73 | TDO2 (0.34) | TDO2CYP11B1CYP11B2NTRK1 | |
| SCHEMBL24921189 | 0.73 | CYP11B1 (0.52) | CYP11B1CYP11B2GRIN1GRIN2B | |
| SCHEMBL24921531 | 0.73 | EGLN1 (0.50) | TDO2EGLN1ALKBH1GRM5RXRA | |
| SCHEMBL24921563 | 0.72 | TDO2 (0.36) | TDO2CYP11B1CYP11B2ALKBH1NTRK1 | |
| SCHEMBL24920403 | 0.71 | HCRTR1 (0.32) | — | |
| SCHEMBL24921536 | 0.71 | MAPT (0.36) | TDO2EGLN1GRM5NTRK1MAPT | |
| SCHEMBL24921503 | 0.70 | ALKBH1 (0.47) | TDO2ALKBH1RXRAGRIN1GRIN2B | |
| SCHEMBL24921580 | 0.70 | MAPKAPK2 (0.50) | MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023006097-A1 | BIFUNCTIONAL CHIMERIC HETEROCYCLIC COMPOUND AND USE THEREOF AS ANDROGEN RECEPTOR DEGRADER | 海创药业股份有限公司 | 2023-02-02 | — | — | WO | disclosed |