Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACACB | O00763 | 8/20 | 0.42 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.42 |
| ▸ | FEN1 | P39748 | 1/20 | 0.42 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.36 |
| ▸ | GRM5 | P41594 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | ACACA | Q13085 | 2/20 | 0.36 |
| ▸ | ABL1 | P00519 | 1/20 | 0.35 |
| ▸ | FDPS | P14324 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30212159 | 0.83 | PIK3CD (0.37) | ALOX5APFEN1P2RX3 | |
| SCHEMBL27234323 | 0.83 | PIK3CD (0.37) | ALOX5APFEN1P2RX3 | |
| SCHEMBL24922347 | 0.78 | ACACB (0.45) | ACACBLMNAMAPTPARP10GRM5 | |
| SCHEMBL27233996 | 0.76 | P2RX3 (0.37) | ALOX5APFEN1P2RX3LMNARAB9A | |
| SCHEMBL24920648 | 0.74 | ACACB (0.46) | ACACBLMNAMAPTPARP10GRM5 | |
| SCHEMBL25002923 | 0.74 | FDPS (0.44) | LMNAMAPTPARP10GRM5NPC1 | |
| SCHEMBL30740799 | 0.74 | RAB9A (0.49) | ALOX5APFEN1P2RX3LMNAMAPT | |
| SCHEMBL30212388 | 0.74 | PIK3CD (0.38) | ACACBP2RX3 | |
| SCHEMBL27234416 | 0.74 | PIK3CD (0.38) | ACACBP2RX3 | |
| SCHEMBL24512733 | 0.73 | MAPT (0.47) | ALOX5APFEN1P2RX3MAPTRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023006097-A1 | BIFUNCTIONAL CHIMERIC HETEROCYCLIC COMPOUND AND USE THEREOF AS ANDROGEN RECEPTOR DEGRADER | 海创药业股份有限公司 | 2023-02-02 | — | — | WO | disclosed |