Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8936566 | 0.86 | — | — | |
| SCHEMBL2487835 | 0.84 | — | — | |
| SCHEMBL2492136 | 0.79 | KDM4E (0.33) | KDM4ETSHRTDP1 | |
| SCHEMBL10868933 | 0.75 | KDM4E (0.31) | KDM4ETSHRTDP1 | |
| SCHEMBL12593544 | 0.75 | — | — | |
| SCHEMBL32669040 | 0.73 | TSHR (0.35) | KDM4ETSHRTDP1 | |
| SCHEMBL866945 | 0.73 | — | — | |
| SCHEMBL7102626 | 0.72 | TSHR (0.33) | KDM4ETSHRTDP1 | |
| SCHEMBL6466894 | 0.72 | LMNA (0.38) | KDM4ETSHRTDP1 | |
| SCHEMBL24421381 | 0.71 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8901170-B2 | Malononitrile compounds | BASF SE (DE) | 2014-12-02 | — | — | US | disclosed |
| EP-2684870-A1 | METHOD FOR PREPARING THIOCARBOXYLIC ACID S-(FLUOROALKYL) ESTER | Sumitomo Chemical Company Limited (JP) | 2014-01-15 | — | — | EP | disclosed |
| CN-101506150-B | Malononitrile compounds | BASF SE | 2013-08-28 | — | — | CN | disclosed |
| US-20100215777-A1 | Malononitrile Compounds | BASF SE (DE) | 2010-08-26 | — | — | US | disclosed |
| EP-2044008-A1 | MALONONITRILE COMPOUNDS | BASF SE (DE) | 2009-04-08 | — | — | EP | disclosed |
| WO-2007147888-A1 | MALONONITRILE COMPOUNDS | BASF SE (DE) | 2007-12-27 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100215777-A1 | Malononitrile Compounds | MAL2, DDT, ACHE | KDM4E 1562/4885TSHR 4062/4885TDP1 4377/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.