Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.44 |
| ▸ | HRH3 | Q9Y5N1 | 7/20 | 0.42 |
| ▸ | HRH4 | Q9H3N8 | 2/20 | 0.42 |
| ▸ | SLC15A2 | Q16348 | 1/20 | 0.40 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.39 |
| ▸ | REN | P00797 | 2/20 | 0.39 |
| ▸ | ANPEP | P15144 | 1/20 | 0.38 |
| ▸ | LNPEP | Q9UIQ6 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27199089 | 0.81 | SLC6A5 (0.66) | SLC6A5SLC15A2RENANPEPLNPEP | |
| SCHEMBL22722181 | 0.81 | HRH3 (0.43) | HRH3HRH4REN | |
| SCHEMBL15185921 | 0.76 | CYP3A4 (0.49) | HRH3HRH4TBXAS1 | |
| SCHEMBL18857393 | 0.76 | QPCT (0.49) | SLC6A5HRH3HRH4TBXAS1 | |
| SCHEMBL18857605 | 0.76 | QPCT (0.49) | SLC6A5HRH3HRH4TBXAS1 | |
| SCHEMBL17206102 | 0.76 | SLC6A5 (0.73) | SLC6A5HRH3SLC15A2 | |
| SCHEMBL18862463 | 0.73 | CYP3A4 (0.43) | SLC6A5HRH3HRH4TBXAS1 | |
| SCHEMBL28220247 | 0.73 | CTSD (0.43) | REN | |
| SCHEMBL23083920 | 0.72 | CCNA2 (0.58) | SLC15A2REN | |
| SCHEMBL18862329 | 0.72 | SLC15A2 (0.51) | SLC6A5SLC15A2RENLNPEP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230035892-A1 | METHODS AND COMPOSITIONS FOR TREATING CANCER | FLAGSHIP PIONEERING, INC. | 2023-02-02 | — | — | US | disclosed |