Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRN | P28799 | 1/20 | 0.37 |
| ▸ | SORT1 | Q99523 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | CXCR4 | P61073 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.34 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.34 |
| ▸ | FAAH | O00519 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | LIPE | Q05469 | 1/20 | 0.33 |
| ▸ | MGLL | Q99685 | 1/20 | 0.33 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.33 |
| ▸ | LTA4H | P09960 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24922128 | 0.81 | KMT2A (0.52) | GRNSORT1KMT2AMEN1CYP1A2 | |
| SCHEMBL27233916 | 0.77 | CHRNA7 (0.39) | GRNSORT1KMT2AMEN1CYP1A2 | |
| SCHEMBL27233918 | 0.77 | CHRNA7 (0.39) | GRNSORT1KMT2AMEN1CYP1A2 | |
| SCHEMBL24921037 | 0.73 | LTA4H (0.30) | LTA4HHRH3 | |
| SCHEMBL27233975 | 0.72 | KMT2A (0.40) | GRNSORT1KMT2AMEN1CYP1A2 | |
| SCHEMBL27233970 | 0.72 | KMT2A (0.40) | GRNSORT1KMT2AMEN1CYP1A2 | |
| SCHEMBL30212531 | 0.72 | NPC1 (0.57) | KMT2AMEN1CYP1A2CYP2C19LMNA | |
| SCHEMBL24922131 | 0.70 | KMT2A (0.39) | KMT2AMEN1CYP1A2CYP2C19LMNA | |
| SCHEMBL30988311 | 0.70 | KMT2A (0.39) | KMT2AMEN1CYP1A2CYP2C19LMNA | |
| SCHEMBL24920613 | 0.70 | ACACB (0.37) | KMT2AMEN1CYP1A2LMNAHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023006097-A1 | BIFUNCTIONAL CHIMERIC HETEROCYCLIC COMPOUND AND USE THEREOF AS ANDROGEN RECEPTOR DEGRADER | 海创药业股份有限公司 | 2023-02-02 | — | — | WO | disclosed |