SCHEMBL2492368

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2492118	0.90	KIF11 (0.43)	ALDH1A1TDP1TSHRLMNAMAPT
	SCHEMBL2494529	0.89	ALDH1A1 (0.43)	ALDH1A1TDP1TSHRLMNAMAPT
	SCHEMBL2489496	0.80	KIF11 (0.35)	ALDH1A1TDP1PTPN1KIF11KDM4E
	SCHEMBL2491343	0.80	ALDH1A1 (0.36)	ALDH1A1TSHRPTPN1KIF11KDM4E
	SCHEMBL2491938	0.79	KIF11 (0.46)	ALDH1A1TDP1TSHRLMNAMAPT
	SCHEMBL2494964	0.77	ALDH1A1 (0.41)	ALDH1A1TDP1TSHRLMNAGAA
	SCHEMBL2489713	0.75	KIF11 (0.59)	ALDH1A1TSHRKIF11RECQLALOX15
	SCHEMBL2489201	0.71	KIF11 (0.42)	ALDH1A1TSHRKIF11ALOX15
	SCHEMBL2492412	0.71	KIF11 (0.46)	TSHRKIF11ALOX15
	SCHEMBL11521694	0.71	ALDH1A1 (0.45)	ALDH1A1TDP1TSHRLMNAMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.