SCHEMBL2494529

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2491938	0.89	KIF11 (0.46)	ALDH1A1TDP1TSHRIDO1RECQL
	SCHEMBL2492368	0.89	ALDH1A1 (0.41)	ALDH1A1TDP1TSHRIDO1RECQL
	SCHEMBL3149801	0.81	ALDH1A1 (0.50)	ALDH1A1TDP1TSHRIDO1RECQL
	SCHEMBL2492118	0.79	KIF11 (0.43)	ALDH1A1TDP1TSHRRECQLLMNA
	SCHEMBL2493496	0.78	KIF11 (0.37)	ALDH1A1TDP1IDO1RECQLL3MBTL1
	SCHEMBL2490811	0.78	ALDH1A1 (0.36)	ALDH1A1TSHRRECQLGAAL3MBTL1
	SCHEMBL2491593	0.76	CA1 (0.41)	ALDH1A1TSHRLMNAGAAL3MBTL1
	Di(Hydroxyethyl)Ether SCHEMBL9694545	0.73	ALDH1A1 (0.50)	ALDH1A1TDP1TSHRIDO1RECQL
	SCHEMBL11514536	0.73	TSHR (0.38)	ALDH1A1TDP1TSHRIDO1RECQL
	SCHEMBL2491921	0.72	KIF11 (0.63)	ALDH1A1TDP1TSHRRECQLGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.