Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 5/20 | 0.47 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.43 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.43 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.43 |
| ▸ | HTR2B | P41595 | 1/20 | 0.43 |
| ▸ | CREBBP | Q92793 | 7/20 | 0.41 |
| ▸ | BMPR1B | O00238 | 1/20 | 0.39 |
| ▸ | BMPR1A | P36894 | 1/20 | 0.39 |
| ▸ | ACVRL1 | P37023 | 1/20 | 0.39 |
| ▸ | ACVR1 | Q04771 | 1/20 | 0.39 |
| ▸ | TLR8 | Q9NR97 | 2/20 | 0.36 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.36 |
| ▸ | DPP4 | P27487 | 1/20 | 0.36 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.36 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.35 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.35 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.35 |
| ▸ | TLR4 | O00206 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22214073 | 0.81 | TRPA1 (0.43) | TRPA1LMNACHRM1SLC6A2ADRA1A | |
| SCHEMBL16528005 | 0.79 | LMNA (0.64) | TRPA1LMNACHRM1SLC6A2ADRA1A | |
| SCHEMBL15889927 | 0.79 | BRD4 (0.50) | BRD4CREBBPBMPR1BBMPR1AACVRL1 | |
| SCHEMBL24924342 | 0.79 | BRD4 (0.40) | BRD4CREBBPBMPR1BBMPR1AACVRL1 | |
| SCHEMBL22641658 | 0.75 | BRD4 (0.47) | BRD4CREBBPBMPR1BBMPR1AACVRL1 | |
| SCHEMBL15889300 | 0.75 | BRD4 (0.47) | BRD4CREBBPBMPR1BBMPR1AACVRL1 | |
| SCHEMBL22214097 | 0.75 | ERCC1 (0.40) | BRD4TRPA1LMNACHRM1SLC6A2 | |
| SCHEMBL24924339 | 0.75 | TRPA1 (0.40) | TRPA1LMNACHRM1SLC6A2ADRA1A | |
| SCHEMBL22448626 | 0.74 | LMNA (0.39) | TRPA1LMNACHRM1SLC6A2ADRA1A | |
| SCHEMBL22214047 | 0.72 | BRD4 (0.45) | BRD4TRPA1LMNACHRM1SLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230020922-A1 | METHODS AND COMPOSITIONS FOR MODULATING SPLICING | SKYHAWK THERAPEUTICS, INC. | 2023-01-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230020922-A1 | METHODS AND COMPOSITIONS FOR MODULATING SPLICING | RBM17, SF3B1, SNRPA1 | BRD4 2641/4885TRPA1 4510/4885LMNA 218/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.